Bilateral Prefrontal Cortex Activation During Sensorimotor Tasks in People with Subacute Stroke – An Exploratory Functional Near-Infrared Spectroscopy Study.
Background: Post-stroke, damage to the prefrontal cortex (PFC) disrupts the neural circuits involved in motor control and sensorimotor integration, which contributes to impaired ankle sensorimotor function. Objective: Apply functional near-infrared spectroscopy (fNIRS) post-stroke to investigate, 1)...
| Publicado en: | NeuroRehabilitation Vol. 57; no. 3; pp. 339 - 352 |
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| Autores principales: | , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Nov2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189650216&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189650216 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: Nov2025 vid: 57 iid: 3 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 189650216 187520155 189650216 189650216 10.1177/10538135251370599 189650216 ppf: 339 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Bilateral Prefrontal Cortex Activation During Sensorimotor Tasks in People with Subacute Stroke – An Exploratory Functional Near-Infrared Spectroscopy Study. aug: au: Luan, Siying Fitzgibbin-Colllins, Laura K Kohli, Sarthak Durand, Nathan Hunter, Susan Fleet, Jamie L Viana, Ricardo Teasell, Robert Peters, Sue affil: Graduate Program in Health and Rehabilitation Sciences, Western University, London, ON, Canada sug: subj: Spectroscopy, Near-Infrared Utilization Prefrontal Cortex Psychomotor Performance Stroke Physiopathology Ankle Physiopathology Treatment Outcomes Evaluation Dominance, Cerebral Physiology Stroke Rehabilitation Human Funding Source Canada Male Female Convenience Sample Adult Middle Age Aged Dorsiflexion Plantarflexion Range of Motion One-Way Analysis of Variance Descriptive Statistics Data Analysis Software Post Hoc Analysis Power Analysis Effect Size Paired T-Tests Hemoglobins Functional Status Sensation Neuroradiography Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Post-stroke, damage to the prefrontal cortex (PFC) disrupts the neural circuits involved in motor control and sensorimotor integration, which contributes to impaired ankle sensorimotor function. Objective: Apply functional near-infrared spectroscopy (fNIRS) post-stroke to investigate, 1) whether PFC activation differed among active and passive dorsiflexion/plantarflexion and somatosensory stimulation of the paretic ankle, 2) differences between hemispheres, and 3) interhemispheric asymmetry and functional outcomes. Methods: In nine participants, bilateral hemodynamic responses of the PFC were collected with fNIRS during active and passive dorsiflexion/plantarflexion and somatosensory stimulation. Sensorimotor function and interhemispheric asymmetry were assessed using the Fugl-Meyer Lower Extremity (FMLE) assessment and laterality index. Results: Across the three tasks, no differences in PFC activation were found within or between hemispheres. There was a potential relationship between interhemispheric asymmetry with the sensory and motor portions of the FMLE, suggesting that greater asymmetry during passive and somatosensory stimulation tasks may be associated with poorer functional outcomes. Conclusions: Our results highlight that ankle sensorimotor functions may not generate different levels of PFC activation in a single hemisphere. The imbalance of PFC activation between the hemispheres from somatosensory and motor input may relate to clinical somatosensory function, which could be a useful measure of recovery. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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