Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan.

In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and...

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Publicado en:Journal of Clinical Pharmacology Vol. 65; no. 12; pp. 1889 - 1900
Autores principales: Nakashima, Akinori, Tsujimoto, Akihide, Saito, Masako, Takeda, Jun, Natori, Makiko, Shoji, Satoshi
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2025
Acceso en línea:Ver este registro en EBSCOhost