Sex-Specific Role of Cognitive Reserve in Activities of Daily Living Recovery After Subacute Stroke.
Objective: This study aimed to investigate the association between cognitive reserve (CR), measured using the Cognitive Reserve Index questionnaire (CRIq), and activities of daily living (ADL) outcomes among patients with stroke during the subacute phase, focusing on sex-related differences in CR an...
| Publicado en: | NeuroRehabilitation Vol. 57; no. 4; pp. 562 - 571 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189710273&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189710273 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: Dec2025 vid: 57 iid: 4 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 189710273 189246484 189710273 189710273 10.1177/10538135251387274 189710273 ppf: 562 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Sex-Specific Role of Cognitive Reserve in Activities of Daily Living Recovery After Subacute Stroke. aug: au: Choi, Young-Ah Nam, So-Young affil: Department of Rehabilitation Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea sug: subj: Sex Factors Cognition Evaluation Activities of Daily Living Evaluation Recovery Stroke Rehabilitation Human South Korea Male Female Middle Age Aged Retrospective Design Record Review Nonexperimental Studies Stroke Patients Tertiary Health Care Questionnaires Scales Semi-Structured Interview Nonparametric Statistics T-Tests Mann-Whitney U Test Chi Square Test Fisher's Exact Test Data Analysis Software NIH Stroke Scale Funding Source Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objective: This study aimed to investigate the association between cognitive reserve (CR), measured using the Cognitive Reserve Index questionnaire (CRIq), and activities of daily living (ADL) outcomes among patients with stroke during the subacute phase, focusing on sex-related differences in CR and their impact on ADL recovery. Results: Ninety-six stroke patients admitted to a rehabilitation ward were included, with demographic and clinical data collected from medical records. No significant sex differences in baseline characteristics were observed. Based on CRIq scores, 70.8% of patients were classified at a medium CR level, with no significant sex difference in composite CRIq scores. However, men scored higher in CRI-Working Activity (CRI-WA), whereas women scored higher in CRI-Leisure Time (CRI-LT). Least Absolute Shrinkage and Selection Operator (LASSO) regression revealed that better functional outcomes at discharge were associated with younger age, higher cognitive reserve, greater initial ADL function, and better motor ability. Additionally, a significant interaction between sex and cognitive reserve indicated a sex-specific effect on ADL recovery. In sex-stratified analyses, CRIq was a significant predictor of Modified Barthel Index (MBI) at discharge in men, along with age, MBI at admission, and Fugl-Meyer Assessment for Upper Extremity (FMA-UE). Conversely, CRIq was not predictive in women, while FMA-LE and MBI at admission were significant predictors. Conclusion: CR is an independent predictor of ADL outcomes, particularly in men, suggesting a sex-specific effect during the subacute phase of stroke. These findings underscore the importance of CR in recovery and support the need for more personalized rehabilitation strategies. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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