Exposure to tebufenpyrad interrupts histo-architecture and fatty acid compositions of carpet shell clam Ruditapes decussatus.
Tebufenpyrad (TUBF) is classified as a pyrazole acaricide and insecticide and is extensively utilized in greenhouse environments in several countries. Nevertheless, limited data exists regarding the potential reproductive toxicity of TUBF, particularly in non-target species. In this study, the fatty...
| Publicado en: | International Journal of Environmental Health Research Vol. 35; no. 12; pp. 3723 - 3735 |
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| Autores principales: | , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189730988&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189730988 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Dec2025 vid: 35 iid: 12 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 189730988 184621890 189730988 189730988 10.1080/09603123.2025.2495196 189730988 ppf: 3723 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Exposure to tebufenpyrad interrupts histo-architecture and fatty acid compositions of carpet shell clam Ruditapes decussatus. aug: au: Mhadhbi, Lazhar Rabeh, Imen Dhibi, Chaima Chelbi, Emna Nechi, Salwa Telahigue, Khaoula affil: LR18ES41 Laboratory. of Ecology, Biology and Physiology of Aquatic Organisms, Faculty of Sciences of Tunis, University Tunis El Manar, Tunis, Tunisia sug: subj: Insecticides Adverse Effects Environmental Exposure Adverse Effects Digestive System Pathology Fatty Acids Analysis Oxidative Stress Evaluation Oxidation-Reduction Evaluation Animal Studies Mollusca Hydrogen Peroxide Analysis Malondialdehyde Analysis Lipid Peroxidation Antioxidants Fatty Acids, Essential Analysis Fatty Acids, Monounsaturated Analysis Fatty Acids, Unsaturated Analysis Fatty Acids, Saturated Analysis Inflammation Chromatography, Gas Glutathione Analysis Comparative Studies Experimental Studies Data Analysis Software One-Way Analysis of Variance Post Hoc Analysis Spearman's Rank Correlation Coefficient Descriptive Statistics ab: Tebufenpyrad (TUBF) is classified as a pyrazole acaricide and insecticide and is extensively utilized in greenhouse environments in several countries. Nevertheless, limited data exists regarding the potential reproductive toxicity of TUBF, particularly in non-target species. In this study, the fatty acid (FA) composition, the histopathology aspects, and redox status were assessed in the digestive gland of the clam Ruditapes decussatus following short-term exposure (96 h) to a series of concentrations (50, 100, and 200 µgL−1) of TUBF. Our findings indicated that TUBF induced oxidative stress, as evidenced by elevated levels of hydrogen peroxide (H2O2), malondialdehyde (MDA), and lipid peroxides (LOOH) in the treated groups. TUBF was also found to disrupt the enzymatic (catalase) and non-enzymatic (reduced glutathione) antioxidant defense systems. Additionally, TUBF was found to disrupt the FA composition. Overall, alterations in saturated (SFA), monounsaturated (MUFA), and polyunsaturated (PUFA) fatty acids, including certain essential FAs (such as LA, ARA, EPA, and DHA), exhibited differential compensatory/adaptive processes in R. decussatus depending on the concentration of TUBF. Furthermore, both examined organs showed various histological impairments, such as lipofuscin accumulation, infiltrative inflammations, and changes in digestive tubules, which provide additional evidence of TUBF toxic effects. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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