Exercise Interventions Improve Frailty in Patients Living in Long-Term Care: A Systematic Review and Meta-Analysis.

The objectives of this study were to examine the impact of exercise training interventions on frailty levels in people who live in long-term care and explore the implementation science outcomes for these interventions. Systematic review and meta-analysis of controlled trials (pre-registered: CRD4202...

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Publicado en:Journal of the American Medical Directors Association Vol. 26; no. 12
Autores principales: Shivgulam, Madeline E., Liu, Haoxuan, Zafar, Zainab, Cheema, Muhammad, Ahmadi, Shirko, Theou, Olga, O'Brien, Myles W.
Formato: meta analysis research systematic review Journal Article
Publicado: Elsevier B.V. Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2025
      vid: 26
      iid: 12
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      pub: Elsevier B.V.
      place: New York, New York
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        10.1016/j.jamda.2025.105945
        189937713
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        atl: Exercise Interventions Improve Frailty in Patients Living in Long-Term Care: A Systematic Review and Meta-Analysis.
      aug:
        au:
          Shivgulam, Madeline E.
          Liu, Haoxuan
          Zafar, Zainab
          Cheema, Muhammad
          Ahmadi, Shirko
          Theou, Olga
          O'Brien, Myles W.
        affil: Geriatric Medicine Research, Nova Scotia Health & Dalhousie University, Halifax, Nova Scotia, Canada
      sug:
        subj:
          Therapeutic Exercise
          Frailty Syndrome Rehabilitation
          Long Term Care
          Training Effect (Physiology)
          Implementation Science
          Outcomes (Health Care)
          Human
          Systematic Review
          Meta Analysis
          Adult
          Embase
          Medline
          CINAHL Database
          Nursing Homes
          Residential Care
          Aged
          Aged, 80 and Over
          Male
          Female
          Phenotype
          Descriptive Statistics
          Confidence Intervals
          Frailty Syndrome Prevention and Control
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: The objectives of this study were to examine the impact of exercise training interventions on frailty levels in people who live in long-term care and explore the implementation science outcomes for these interventions. Systematic review and meta-analysis of controlled trials (pre-registered: CRD42024542751). Adults residing in long-term care settings who are enrolled in exercise training interventions. Sources (Scopus, EMBASE, MEDLINE, CINAHL, Academic Search Premier) were searched in May 2024. Studies were included if they conducted an exercise intervention and assessed frailty via a validated frailty assessment tool. The between-group effect size of change in frailty (intervention vs control) was calculated as the standardized mean difference (SMD) using a random effects model. Six studies conducted in nursing homes (n = 1), residential care (n = 1), and long-term care (n = 4) included 191 intervention [age: 81.9 (range: 73.3–86.7) years; n = 115 reported women] and 205 control [age: 81.3 (range: 77.8–86.4) years; n = 106 reported women] participants. Studies included the frailty phenotype (n = five-sixths) or the Study of Osteoporotic Fractures Index (n = one-sixth). The types of training were heterogeneous, but interventions were 3.2 ± 1.1 (range: 2–5) times/week for 44 ± 8.9 (40–60) minutes/session for 23.6 ± 17.7 (6–52) weeks. Most interventions improved frailty compared with controls (n = five-sixths), with the one study observing no change in the intervention, but the control group worsened. A large effect size of the intervention relative to controls was observed (SMD: 1.83; 95% confidence intervals: 0.66–2.99). Implementation outcomes were scarcely reported, but were generally positive when reported (high adherence, high retention rate, low adverse events, strong feasibility). This review and meta-analysis support that exercise training is an effective model of improving frailty levels among older adults in long-term care. Strategies to address the practical aspects of these programs are needed, but this study emphasizes that structured exercise should be a crucial aspect of long-term care.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        Journal Article
      ougenre: Article
    language: English
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