Revolutionizing Lung Cancer Detection: A High‐Accuracy Machine Learning Framework for Early Diagnosis.

Lung cancer is a deadly disease. According to a report of 2024, it is the primary reason for 1.82 million deaths. Given the high disease burden, early detection of lung cancer is crucial for improving survival rates and implementing effective strategies. This paper is aimed at conducting a systemati...

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Published in:BioMed Research International Vol. 2025; pp. 1 - 27
Main Authors: Ali, Tahir Muhammad, Mir, Azka, Rehman, Attique Ur, Humayun, Mamoona, Shaheen, Momina, Alshammari, Rafeef Taresh Suliman, Wesley, Hannah
Format: equations & formulas pictorial research systematic review tables/charts Journal Article
Published: Wiley-Blackwell 12/12/2025
Online Access:View this record in EBSCOhost
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      dt: 12/12/2025
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/bmri/9961773
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        atl: Revolutionizing Lung Cancer Detection: A High‐Accuracy Machine Learning Framework for Early Diagnosis.
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          Ali, Tahir Muhammad
          Mir, Azka
          Rehman, Attique Ur
          Humayun, Mamoona
          Shaheen, Momina
          Alshammari, Rafeef Taresh Suliman
          Wesley, Hannah
        affil: Department of Computer Science,, Gulf University for Sciences and Technology,, Mubarak Al-Abdullah, Kuwait
      sug:
        subj:
          Lung Neoplasms Diagnosis
          Machine Learning
          Early Detection of Cancer
          Prediction Models
          Human
          Systematic Review
          PubMed
          Funding Source
          Descriptive Statistics
          Decision Trees
          Logistic Regression
          Random Forest
          Support Vector Machine
      ab: Lung cancer is a deadly disease. According to a report of 2024, it is the primary reason for 1.82 million deaths. Given the high disease burden, early detection of lung cancer is crucial for improving survival rates and implementing effective strategies. This paper is aimed at conducting a systematic literature review and developing a highly accurate framework for predicting lung cancer effectively. Tollgate methodology has been used for systematic literature review, and quality assessment criteria were applied to select published articles relevant to the research questions. The paper investigates the effectiveness of machine learning in identifying patterns relevant to lung cancer prediction (Q1), examines the pros and cons of current predictive systems (Q2), compares the use of artificial intelligence in lung cancer prediction with traditional methods (Q3), and identifies key features that distinguish lung cancer from patient symptoms (Q4). Machine learning techniques were employed for the proposed framework. Two publicly available, distinct datasets containing clinical features were obtained. Then, the SelectKBest method was used for feature selection, and SMOTE was used to handle class imbalance. Our proposed framework includes a voting ensemble with random forest, support vector machine, and logistic regression with cross‐validation. The results indicate an accuracy of 99% and 92.5% for the first and second datasets, respectively. This study′s systematic literature review, based on four research questions and a machine learning model, exhibits high accuracy in predicting lung cancer.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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