Effect of Regular Exercise on Cognitive Frailty in the Elderly: A Systematic Review.
Objectives: As one of the common senile syndromes characterized by the co-existence of physical frailty and cognitive impairment without dementia, the occurrence of cognitive frailty (CF) increases the risk of adverse health outcomes in older adults. However, its reversibility has attracted the inte...
| Publicado en: | Experimental Aging Research Vol. 52; no. 1; pp. 30 - 57 |
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| Autores principales: | , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan/Feb2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190232263&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190232263 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0361073X 1HO jtl: Experimental Aging Research issn: 0361073X maglogo: N pubinfo: dt: Jan/Feb2026 vid: 52 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 190232263 184070269 190232263 190232263 10.1080/0361073X.2025.2485619 190232263 ppf: 30 ppct: 27 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effect of Regular Exercise on Cognitive Frailty in the Elderly: A Systematic Review. aug: au: Ji, Wenting Sun, Liwei Geng, Qian Zheng, Guohua affil: Graduate School, Shanghai University of Traditional Chinese Medicine, China sug: subj: Cognition Disorders Therapy Therapeutic Exercise Exercise Physiology Evaluation Frailty Syndrome Therapy Training Effect (Physiology) Community Living Psychosocial Factors Human Systematic Review Funding Source Male Female Middle Age Aged Aged, 80 and Over Frail Elderly Psychosocial Factors Checklists Frailty Syndrome Complications Cochrane Library PubMed China Confidence Intervals Descriptive Statistics Data Analysis Software Task Performance and Analysis Executive Function Evaluation Physical Activity Evaluation Phenotype Balance, Postural Functional Status Gait Analysis Quality of Life Psychological Tests Processing Speed Evaluation Grip Strength Exercise Intensity Healthy Aging Physical Performance Resistance Training Aerobic Exercises Balance Training, Physical Step Exergames Walking Speed Mindfulness Tai Chi Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objectives: As one of the common senile syndromes characterized by the co-existence of physical frailty and cognitive impairment without dementia, the occurrence of cognitive frailty (CF) increases the risk of adverse health outcomes in older adults. However, its reversibility has attracted the interest of researchers in the search for effective interventions. A growing number of studies have been conducted to investigate the effect of regular physical exercise intervention on cognitive frailty in older adults with CF, but findings remain inconclusive. This study aimed to synthesize the pooled effect of current regular exercise intervention in community-dwelling older adults with cognitive frailty. Methods: Nine electronic databases (Cochrane Library, PubMed, EBSCOHost, Web of Science, Scopus, CNKI, Wanfang Database, VIP and SinoMed) were searched from their inception to 15 May, 2024. The Cochrane risk-of-bias tool (ROB 2) for RCTs was applied to assess the methodological quality. The mean difference or standardized mean difference with 95% CIs was calculated by using Stata 18.0. Results: Seventeen eligible studies involving a total of 2239 participants were included. The pooled results showed that older adults with CF in the intervention group had significant improvement in global cognitive function performance (MMSE scores: MD = 1.93 95% CI: 1.02 to 2.85, p <.0001, and MoCA scores: MD = 3.24, 95% CI: 1.57 to 4.91, p <.0001), executive function (time of TMT-B test: MD = -20.73, 95% CI: −33.96 to −7.50, p =.002), physical frailty state (Fried frailty phenotype scores: MD = -1.48, 95% CI: -2.37 to −0.58, p =.001, and EFS scores: MD = −0.81 points, 95% CI: -1.13 to −0.49, p <.0001), grip strength (SMD = 0.92, 95% CI: 0.15 to 1.07, p =.02), gait and balance (time of TUG: MD = −2.62, 95% CI: −4.12 to −1.11, p =.001), balance (BBS scores: MD = 8.56, 95% CI:- 3.37 to 13.75, p =.001) and quality of life (SMD = 0.75, 95% CI: 0.30 to 1.21, p =.001). Conclusions: More than eight weeks of regular exercise interventions may improve global cognitive function and physical frailty status, but the effect on specific domains of cognitive or physical function needs further study to confirm. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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