<italic>Physcomitrium patens</italic>: an emerging model for autophagy study.

<italic>Physcomitrium patens</italic> (formerly <italic>Physcomitrella patens</italic>), a model moss species, has emerged as an invaluable system for studying autophagy in plants. This review highlights the unique advantages of <italic>P. patens</italic> for autophagy research, including its effici...

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Publicado en:Protoplasma p. 1
Autor principal: Sakil, Md Arif
Formato: Journal Article
Publicado: Springer Nature Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2025
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        10.1007/s00709-025-02148-9
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        atl: <italic>Physcomitrium patens</italic>: an emerging model for autophagy study.
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        au: Sakil, Md Arif
        affil: Department of Biochemistry and Molecular Biology, Agricultural University
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      ab: <italic>Physcomitrium patens</italic> (formerly <italic>Physcomitrella patens</italic>), a model moss species, has emerged as an invaluable system for studying autophagy in plants. This review highlights the unique advantages of <italic>P. patens</italic> for autophagy research, including its efficient homologous recombination in mitotic cells, simple body plan, haploid-presiding life cycle, and accessibility to microscopic observation. I discuss recent advances in understanding autophagy mechanisms in <italic>P. patens</italic>, particularly focusing on the role of core autophagy-related (ATG) genes in growth, development, stress responses, and cell death. The characterization of autophagy-deficient mutants revealed unexpected roles of autophagy in promoting cell death under oxidative stress and desiccation, in contrast with classical survival functions. I also examine the conservation and divergence of the autophagy machinery between mosses and vascular plants, emphasizing how <italic>P. patens</italic> bridges evolutionary gaps in our understanding of plant autophagy. Finally, I outline future perspectives on the use of this model system to address fundamental questions about selective autophagy, autophagosome dynamics, and the integration of autophagy with developmental programs.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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