Juvenile Fibroadenoma Detected at 2 Years and Rapid Growth at Thelarche: Case Report and Literature Review.
Juvenile fibroadenoma typically is seen in the adolescent patient and has distinctive clinical and histopathological features that are related to the early onset of the benign tumor. Only rarely can juvenile fibroadenoma occur as a prepubertal lesion or may be detected earlier in childhood, raising...
| Publicado en: | Breast Cancer: Basic & Clinical Research Vol. 19; pp. 1 - 8 |
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| Autores principales: | , , |
| Formato: | case study diagnostic images pictorial Journal Article |
| Publicado: |
Sage Publications Inc.
9/6/2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190387422&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190387422 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11782234 B078 jtl: Breast Cancer: Basic & Clinical Research issn: 11782234 maglogo: Y pubinfo: dt: 9/6/2025 vid: 19 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 190387422 190387422 190387422 10.1177/11782234241306209 190387422 ppf: 1 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Juvenile Fibroadenoma Detected at 2 Years and Rapid Growth at Thelarche: Case Report and Literature Review. aug: au: Schaefgen, Benedikt Buchen, Stephanie Sinn, Hans-Peter affil: Frauenklinik, Sektion Senologie, Universitätsklinikum Heidelberg, Heidelberg, Germany sug: subj: Neoplasms, Fibrous Tissue Diagnosis Neoplasms, Fibrous Tissue Surgery Breast Neoplasms Diagnosis Breast Neoplasms Surgery Neoplasms, Fibrous Tissue Pathology Breast Neoplasms Pathology Puberty Child Female Histology Breast Neoplasms Symptoms Neoplasms, Fibrous Tissue Symptoms Multidisciplinary Care Team Breast Ultrasonography Biopsy Pain Etiology Erythema Etiology Clindamycin Therapeutic Use Pediatric Surgery Child: 6-12 years Female ab: Juvenile fibroadenoma typically is seen in the adolescent patient and has distinctive clinical and histopathological features that are related to the early onset of the benign tumor. Only rarely can juvenile fibroadenoma occur as a prepubertal lesion or may be detected earlier in childhood, raising questions about differential diagnosis and management of the lesion. We present a case of very early first manifestation of juvenile fibroadenoma in a 2-year-old patient. Under clinical observation and conservative management over a 7-year period, there was no progression. At the age of 9 years, rapid growth of the lesion occurred causing clinical symptoms. Complete surgical excision resulted in a good clinical outcome. Histologically, the diagnosis of juvenile fibroadenoma was made. In summary, juvenile fibroadenoma is the most common breast neoplasia in adolescents and may cause excessive unilateral growth resulting in gross asymmetry and pain. However, it can be detectable in early childhood and after a dormant period of several years, as in this case, lead to sudden massive growth at the onset of puberty. The clinical management should include an interdisciplinary treatment approach with gynecology, pediatrics, and pediatric surgery to balance the risks and benefits of conservative management. Surgical removal can be safely postponed until it becomes necessary due to clinical symptoms. pubtype: Academic Journal doctype: case study diagnostic images pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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