Implementation of IOM in Uganda Utilizing the EPIS Framework: Report of a Symbiotic Collaboration.

Objectives: Low- and lower-middle-income countries (LMICs) bear a disproportionately high burden of neurosurgical disease while facing severe shortages of trained neurosurgeons and anesthesiologists. Access to advanced technologies such as intraoperative neuromonitoring (IONM), crucial for complex n...

Full description

Bibliographic Details
Published in:Journal of Central Nervous System Disease Vol. 17; pp. 1 - 8
Main Authors: Montejano, Julio, Nantongo, Betty, Klumpp, Tessa, Djoyumm, Teguo Daniel, Lahiri, Joshua, Watiti, Daniel, Okechi, Humphrey, Wegoye, Emmanuel, Simmons, Colby
Format: tables/charts Journal Article
Published: Sage Publications Inc. 12/17/2025
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190402202&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 190402202
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        11795735
        B3L8
      jtl: Journal of Central Nervous System Disease
      issn: 11795735
      maglogo: Y
    pubinfo:
      dt: 12/17/2025
      vid: 17
      pid: 344
      pub: Sage Publications Inc.
      place: Thousand Oaks, California
    artinfo:
      ui:
        190402202
        190402202
        190402202
        10.1177/11795735251408597
        190402202
      ppf: 1
      ppct: 7
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Implementation of IOM in Uganda Utilizing the EPIS Framework: Report of a Symbiotic Collaboration.
      aug:
        au:
          Montejano, Julio
          Nantongo, Betty
          Klumpp, Tessa
          Djoyumm, Teguo Daniel
          Lahiri, Joshua
          Watiti, Daniel
          Okechi, Humphrey
          Wegoye, Emmanuel
          Simmons, Colby
        affil: Department of Anesthesiology, University of Colorado, Aurora, CO, USA
      sug:
        subj:
          Neurosurgery In Infancy and Childhood
          Intraoperative Monitoring Uganda
          Program Development
          Program Implementation
          Implementation Science
          Conceptual Framework
          Hospitals, Pediatric Uganda
          Uganda
          Colleges and Universities Colorado
          Interinstitutional Relations
          International Relations
          Collaboration
          Colorado
          Neurophysiology
          Pediatric Surgery
          Patient Safety
          Evoked Potentials, Somatosensory
          Evoked Potentials, Motor
          Electromyography
          Resource-Limited Settings
          Anesthesia
          Protocols
          Child
          Quality Improvement
          Child: 6-12 years
      ab: Objectives: Low- and lower-middle-income countries (LMICs) bear a disproportionately high burden of neurosurgical disease while facing severe shortages of trained neurosurgeons and anesthesiologists. Access to advanced technologies such as intraoperative neuromonitoring (IONM), crucial for complex neurosurgical procedures, is virtually nonexistent due to infrastructural, educational, and financial barriers. This study describes the development and implementation of Uganda's first IONM program at Cure Children's Hospital of Uganda (CCHU), using the well validated Exploration, Preparation, Implementation, and Sustainment (EPIS) framework. Methods: In collaboration with the University of Colorado, a standardized non-traditional training pathway was created, combining remote and in-person instruction in neurophysiology, technical IONM applications, and anesthetic considerations. Over a 3-year period, the program enabled CCHU to safely perform more than 80 complex pediatric neurosurgical cases across 2 years, incorporating modalities such as somatosensory evoked potentials (SSEPs), motor evoked potentials (MEPs), and electromyography (EMG). Surgical and patient outcomes were not tracked for the purposes of this implementation study. Results: Between March 2022 and October 2024, 80 surgeries were performed at CCHU that made use of IONM technologies. The vast majority of the surgeries were intracranial and included one awake tumor resection with direct cortical mapping (DCS). A smaller subsect of patients underwent spine surgery for either tumor removal or correction of spinal cord tethering. Due to the difficulty in patient outreach many patients were lost to follow-up, however, efforts are being made to track patients and examine their clinical outcomes. Conclusion: Despite resource limitations, this initiative demonstrated that IONM can be effectively integrated into LMIC healthcare settings, improving surgical safety and outcomes while contributing to local workforce development. The success of this program underscores the value of international partnerships and implementation science in bridging global neurosurgical disparities and suggests a scalable model for future adoption across similar contexts.
      pubtype: Academic Journal
      doctype:
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N