만성 손발톱주위염과 내향성 손발톱: 병리기전 및 치료 전략.

Purpose: Chronic paronychia and ingrown nails (onychocryptosis) are common nail disorders that cause pain, functional impairment, and reduced quality of life. They occur frequently in both dermatology and primary care settings. Effective management requires an understanding of the underlying mechani...

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Publicado en:Journal of the Korean Medical Association / Taehan Uisa Hyophoe Chi Vol. 68; no. 11; pp. 743 - 752
Autor principal: Lee, Young Bok
Formato: pictorial review tables/charts Journal Article
Publicado: Korean Medical Association Nov2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2025
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      pub: Korean Medical Association
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        atl: 만성 손발톱주위염과 내향성 손발톱: 병리기전 및 치료 전략.
      aug:
        au: Lee, Young Bok
        affil: Department of Dermatology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
      sug:
        subj:
          Paronychia Etiology
          Paronychia Pathology
          Paronychia Prevention and Control
          Nails, Ingrown Etiology
          Nails, Ingrown Pathology
          Nails, Ingrown Prevention and Control
          Medical Practice, Evidence-Based
          Physicians
          Counseling
          Paronychia Symptoms
          Nails, Ingrown Symptoms
          Inflammation Prevention and Control
          Paronychia Drug Therapy
          Nails, Ingrown Drug Therapy
          Adrenal Cortex Hormones Therapeutic Use
          Antifungal Agents Therapeutic Use
          Patient Centered Care
      ab: Purpose: Chronic paronychia and ingrown nails (onychocryptosis) are common nail disorders that cause pain, functional impairment, and reduced quality of life. They occur frequently in both dermatology and primary care settings. Effective management requires an understanding of the underlying mechanisms and available treatment approaches. This review summarizes the etiopathogenesis, clinical features, and evidence-based management of chronic paronychia and ingrown nails, providing practical guidance for physicians. Current Concepts: Chronic paronychia is a multifactorial inflammation of the nail folds persisting for more than 6 weeks, typically initiated by disruption of the cuticle barrier. This disruption allows moisture, irritants, and microbes to penetrate the periungual area, resulting in chronic inflammation, fibrosis, and retraction. Candida species are often isolated but function predominantly as secondary colonizers. Environmental triggers such as frequent wet work, artificial nails, and anticancer therapies (including epidermal growth factor inhibitors and taxanes) can further compromise the periungual barrier. Ingrown nails arise from penetration of the nail plate into, or overgrowth of, hypertrophic folds. These changes are promoted by improper trimming, tight footwear, anatomical predisposition, systemic disease, or trauma. Discussion and Conclusion: Management primarily aims to remove triggers, control inflammation, and restore the periungual barrier. Early stages usually respond to conservative measures, including topical corticosteroids, calcineurin inhibitors, antifungal agents, footwear modification, nail splinting, and patient education. Severe or refractory cases may require surgical intervention, such as square flap excision for chronic paronychia or partial nail avulsion with phenol matricectomy and soft tissue resection for ingrown nails. Individualized therapy can improve outcomes, minimize recurrence, and enhance quality of life.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: Korean
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