Pediatric Sinonasal Adenocarcinoma with Anterior Cranial Fossa Extension: Surgical Nuances, Novel Skull Base Reconstruction, and Ajuvant Therapy.
Abstract: Sinonasal adenocarcinoma (SAC) is an exceptionally rare malignancy in the pediatric population, especially with extensive anterior cranial fossa involvement. Optimal management requires meticulous surgical planning and a multidisciplinary approach. We present a 16-year-old male with progre...
| Publicado en: | Journal of Pediatric Neurosciences Vol. 20; no. 4; pp. 221 - 230 |
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| Autores principales: | , , , , , , , |
| Formato: | case study diagnostic images pictorial tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Oct-Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190406977&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190406977 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18171745 1KUH jtl: Journal of Pediatric Neurosciences issn: 18171745 maglogo: N pubinfo: dt: Oct-Dec2025 vid: 20 iid: 4 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 190406977 190406977 190406977 10.4103/jpn.jpn_59_25 190406977 ppf: 221 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Pediatric Sinonasal Adenocarcinoma with Anterior Cranial Fossa Extension: Surgical Nuances, Novel Skull Base Reconstruction, and Ajuvant Therapy. aug: au: Maste, Praful S. Soumya, S. Gautam, Abhishek Havaldar, Rajesh Kotrashetti, Sharadindu M. Sharma, Ela Nanjegowda, Nandeesh B. Hattiholi, Virupaxi affil: Department of Neurosurgery, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India sug: subj: Adenocarcinoma Surgery Adenocarcinoma Pathology Paranasal Sinus Neoplasms Surgery Paranasal Sinus Neoplasms Pathology Skull Pathology Skull Surgery Endoscopy Methods Craniotomy Methods Surgery, Reconstructive Methods Radiotherapy, Adjuvant Methods Treatment Outcomes Male Adolescence Nasal Cavity Pathology Nasal Cavity Surgery Orbit Pathology Orbit Surgery Embolization, Therapeutic Methods Hemostasis, Surgical Methods Surgical Mesh Utilization Titanium Therapeutic Use Fascia Transplantation Tomography, X-Ray Computed Methods Magnetic Resonance Imaging Methods Histology Methods Immunohistochemistry Methods Biopsy Methods Adolescent: 13-18 years Male ab: Abstract: Sinonasal adenocarcinoma (SAC) is an exceptionally rare malignancy in the pediatric population, especially with extensive anterior cranial fossa involvement. Optimal management requires meticulous surgical planning and a multidisciplinary approach. We present a 16-year-old male with progressive nasal obstruction, epistaxis, facial swelling, anosmia, and proptosis. Imaging revealed a large, lobulated mass originating in the nasal cavity with intracranial and orbital extension. A combined transcranial and endoscopic trans-nasal resection was performed. Reconstruction of the skull base utilized a titanium mesh buttress with pericranial and fascia lata grafts. Histopathology confirmed low-grade, non-intestinal-type SAC. Two small residual lesions over the nasal dorsum were excised post-operatively. The patient subsequently received adjuvant radiotherapy. Follow-up imaging and endoscopic surveillance confirmed disease-free status at 6 months. This case highlights the complexity of pediatric SAC with skull base invasion. A combined surgical approach with innovative skull base reconstruction and timely adjuvant therapy can achieve effective disease control. pubtype: Academic Journal doctype: case study diagnostic images pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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