Descriptive Epidemiology of Klebsiella spp. Urinary Tract Infections in Central Africa.

Objective: Urinary tract infections are the most common bacterial infections encountered in clinical practice. Among the pathogens responsible, bacteria of the Klebsiella spp. are the second most frequently isolated uropathogenic agents worldwide. These bacteria are constantly evolving, both epidemi...

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Publicado en:BioMed Research International Vol. 2025; pp. 1 - 16
Autores principales: Mayombo Ngoussou, Evrard, Mounioko, Franck, Mundunge, Mambu, Mabika Mabika, Rolande, Zong Minko, Ornella, Ondjiangui, Léonce Fauster, Yala, Jean Fabrice, Fröhlich, Eleonore
Formato: meta analysis pictorial research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell 12/21/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 12/21/2025
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Descriptive Epidemiology of Klebsiella spp. Urinary Tract Infections in Central Africa.
      aug:
        au:
          Mayombo Ngoussou, Evrard
          Mounioko, Franck
          Mundunge, Mambu
          Mabika Mabika, Rolande
          Zong Minko, Ornella
          Ondjiangui, Léonce Fauster
          Yala, Jean Fabrice
          Fröhlich, Eleonore
        affil: Bacteriology Laboratory,, Medical Analysis Research Unit,, Interdisciplinary Center of Medical Research of Franceville (CIRMF),, Franceville, Gabon
      sug:
        subj:
          Urinary Tract Infections Epidemiology
          Klebsiella Infections Epidemiology
          Human
          Africa, Central
          Systematic Review
          Meta Analysis
          PubMed
          Prevalence
          Geographic Factors
          Maps
          Sex Factors
          Checklists
      ab: Objective: Urinary tract infections are the most common bacterial infections encountered in clinical practice. Among the pathogens responsible, bacteria of the Klebsiella spp. are the second most frequently isolated uropathogenic agents worldwide. These bacteria are constantly evolving, both epidemiologically and in terms of the development of antimicrobial resistance. In Central Africa, available data on the spread of Klebsiella spp. are mainly derived from isolated studies, making it difficult to obtain an overview of their epidemiology in the subregion. Consequently, these systematic review and meta‐analysis are aimed at estimating the pooled prevalence of urinary tract infections in Central Africa and to describe the epidemiology of the Klebsiella spp. strains responsible for these infections. Methods: Relevant articles were searched in the SCOPUS, PubMed, and Google Scholar databases. The study selection process was conducted in accordance with the PRISMA flowchart recommendations. Systematic review and meta‐analysis were used to summarize data on urinary tract infections. Prevalence was determined and visualized using a forest plot with R software Version 4.4.1. Also, finally, geographical mapping of the data distribution was carried out using QGIS software (Version 3.34.15‐Prizren). Result: Out of all the articles retrieved, 34 studies were deemed eligible for this analysis. The overall pooled prevalence of urinary tract infections in Central Africa was estimated at 28% (95% IC: 28, 29). The overall isolation rate of Klebsiella spp. responsible for urinary tract infections was 12% (95% IC: 11, 12). Analysis of the distribution of Klebsiella spp. isolation rates in urinary tract infections across Central Africa revealed variability by country, ranging from 10% to 25%. The species Klebsiella pneumoniae was the most frequently isolated, present in 96.15% of the studies. Furthermore, Klebsiella spp. strains responsible for urinary tract infections were predominantly identified in females, with an overall isolation rate of 82.23%, compared to 17.77% in males.
      pubtype: Academic Journal
      doctype:
        meta analysis
        pictorial
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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