Near Infrared Spectroscopy as a Diagnostic Tool for Screening of Intracranial Hematomas; A Systematic Review and Meta-Analysis.
Introduction: Evidence supports the clinical applicability of near-infrared spectroscopy (NIRS) in intracranial hematoma detection in prehospital settings. This systematic review and meta-analysis aimed to determine the diagnostic yield of NIRS for detecting intracranial hematoma in traumatic brain...
| Publicado en: | Archives of Academic Emergency Medicine Vol. 13; no. 1; pp. 1 - 14 |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Shahid Beheshti University of Medical Sciences
2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190500656&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190500656 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 26454904 MFMK jtl: Archives of Academic Emergency Medicine issn: 26454904 maglogo: N pubinfo: dt: 2025 vid: 13 iid: 1 pid: 87963 pub: Shahid Beheshti University of Medical Sciences artinfo: ui: 190500656 190500656 190500656 10.22037/aaem.v13i1.2411 190500656 ppf: 1 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Near Infrared Spectroscopy as a Diagnostic Tool for Screening of Intracranial Hematomas; A Systematic Review and Meta-Analysis. aug: au: Zarei, Hamed Zarrin, Amirali Janmohamadi, Mahrokh Saadatipour, Narges Yarahmadi, Mobina Moeini, Mohammadmobin Ardekani, Shireen Shams Safdarian, Ali Vazirizadeh-Mahabadi, Mohammadhossein Babaei, Mohammadhossein Bagheri, Negin Gholipour, Amirhossein Azadi, Mohammadreza Parvari, Soraya Azimi, Amir affil: Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran. sug: subj: Spectroscopy, Near-Infrared Utilization Hematoma, Subdural Diagnosis Diagnostic Imaging Methods Human Systematic Review Meta Analysis PubMed Medline Embase Tomography, X-Ray Computed Magnetic Resonance Imaging Professional Practice, Evidence-Based Emergency Medical Services Emergency Service Point-of-Care Testing Brain Concussion Diagnosis ab: Introduction: Evidence supports the clinical applicability of near-infrared spectroscopy (NIRS) in intracranial hematoma detection in prehospital settings. This systematic review and meta-analysis aimed to determine the diagnostic yield of NIRS for detecting intracranial hematoma in traumatic brain injury (TBI) patients. Methods: A systematic search was performed in July 2024 in Medline, Embase, Scopus, and Web of Science databases. We included studies that evaluated the diagnostic performance of NIRS in detecting intracranial hematoma in both adult and pediatric patients suspected of TBI in prehospital or emergency settings, using brain computed tomography (CT) scan or magnetic resonance imaging as the gold standard. Results: Eighteen studies enrolling 2979 patients were included. NIRS exhibited an Area Under the Curve (AUC) of 0.91 (95% confidence interval [CI]: 0.88, 0.93), with a sensitivity of 0.86 (95% CI: 0.78, 0.91), and specificity of 0.82 (95% CI: 0.72, 0.89) across all age groups. In children, the results demonstrated an AUC of 0.92 (95% CI: 0.89, 0.94), sensitivity of 0.95 (95% CI: 0.21, 1.00), and specificity of 0.81 (95% CI: 0.65, 0.91). Among adults, the AUC was 0.91 (95% CI: 0.88, 0.93), with sensitivity and specificity of 0.86 (95% CI: 0.78, 0.92) and 0.83 (95% CI: 0.70, 0.91), respectively. Performance improved when NIRS was operated by non-physicians (AUC = 0.94 [95% CI: 0.91, 0.96], sensitivity = 0.90 [95% CI: 0.79, 0.95], specificity = 0.85 [95% CI: 0.71, 0.93]) compared to physicians (AUC = 0.90 [95% CI: 0.87, 0.92], sensitivity = 0.88 [95% CI: 0.77, 0.94], specificity = 0.75 [95% CI: 0.59, 0.76]). Patients’ age group and operator type were identified as potential sources of heterogeneity. Sensitivity analyses confirmed the robustness of the findings, particularly in mild TBI cases and studies implementing a OD > 0.2 as the threshold for a positive NIRS result. Conclusion: NIRS proves to be an effective diagnostic tool for detecting traumatic intracranial hematoma in both pediatric and adult groups, with high sensitivity and specificity. Its utility in prehospital triage, operated by physicians or paramedics, underscores its potential for broader clinical application. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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