Independent Predictors of Heat-Related Illness-Induced Acute Respiratory Failure: A Multicenter Cross-sectional Study.

Introduction:Acute respiratory failure (ARF) is a critical complication of heat-related illness (HRI). This study aimed to identify predictors of HRI-induced ARF in patients presenting to the emergency department (ED). Methods: Patients aged 20 years and above diagnosed with HRI (ICD-9-CM code 992 o...

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Published in:Archives of Academic Emergency Medicine Vol. 13; no. 1; pp. 1 - 10
Main Authors: Kuo, Wan-Yin, Huang, Chien-Cheng, Hsu, Chien-Chin, Lin, Hung-Jung, Su, Shih-Bin, Liu, Chung-Feng, Sung, Mei-I, Chen, Chi-An, Guo, How-Ran
Format: research tables/charts Journal Article
Published: Shahid Beheshti University of Medical Sciences 2025
Online Access:View this record in EBSCOhost
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        atl: Independent Predictors of Heat-Related Illness-Induced Acute Respiratory Failure: A Multicenter Cross-sectional Study.
      aug:
        au:
          Kuo, Wan-Yin
          Huang, Chien-Cheng
          Hsu, Chien-Chin
          Lin, Hung-Jung
          Su, Shih-Bin
          Liu, Chung-Feng
          Sung, Mei-I
          Chen, Chi-An
          Guo, How-Ran
        affil: School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
      sug:
        subj:
          Heat Stress Disorders Complications
          Acute Disease Risk Factors
          Respiratory Failure Risk Factors
          Risk Assessment
          Emergency Service
          Human
          Male
          Female
          Funding Source
          Emergency Patients
          Logistic Regression
          Comparative Studies
          Prevalence
          Glasgow Coma Scale
          Scales
          Respiration Evaluation
          Body Temperature
          Hypertension
          Cerebrovascular Disorders
          Pulmonary Disease, Chronic Obstructive
          Association (Research)
          Multicenter Studies
          Cross Sectional Studies
          Record Review
          Hospitals
          Taiwan
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Pearson's Correlation Coefficient
          Chi Square Test
          Fisher's Exact Test
          Multiple Logistic Regression
          Univariate Statistics
          Odds Ratio
          Confidence Intervals
          Correlation Coefficient
          Goodness of Fit Chi Square Test
          Descriptive Statistics
          Data Analysis Software
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Introduction:Acute respiratory failure (ARF) is a critical complication of heat-related illness (HRI). This study aimed to identify predictors of HRI-induced ARF in patients presenting to the emergency department (ED). Methods: Patients aged 20 years and above diagnosed with HRI (ICD-9-CM code 992 or ICD-10 code T67) who visited the EDs of the three hospitals in Tainan, Taiwan between January 2010 and October 2021, were included. Demographic characteristics, comorbidities, and laboratory data were collected. Logistic regression models using the backward elimination method were constructed to identify the independent predictors of HRI-induced ARF. Results: 820 patients with the mean age of 50.0 ± 18.4 years were studied (80.0% male). 29 (3.5%) cases experienced ARF. Patients with ARF were less likely to walk on arrival compared to those without it (27.6% vs. 61.8%, p < 0.001). Additionally, they had higher prevalence of Glasgow Coma Scale (GCS) scores ≤ 8 (p = 0.003), respiratory rate > 20 breaths/min (p < 0.001), body temperature ≥ 40°C (p < 0.001), hypertension (p = 0.001), cerebrovascular disease (p = 0.001), and chronic obstructive pulmonary disease (p = 0.042). The multivariable logistic regression revealed that body temperature ≥ 40 °C on arrival (odds ratio (OR): 7.76; 95% confidence interval (CI): 3.14–19.15), an initial respiratory rate > 20 breaths/min (OR: 8.19; 95% CI: 3.48–19.24), and history of hypertension (OR: 3.38; 95% CI: 1.52–7.52) were predictors of HRI-induced ARF. Conclusion: Elevated body temperature, respiratory rate, and a history of hypertension were key predictors of ARF in HRI patients, aiding in patient stratification for emergency care.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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