Chest Compression Synchronized Mechanical Ventilation Modes for Cardiac Arrest; A Scoping Review.

Introduction: Chest Compression Synchronized Ventilation (CCSV) is a novel approach aimed at optimizing gas exchange and hemodynamics during cardiopulmonary resuscitation (CPR). However, its clinical value, safety profile and implementation barriers remain unclear. This study aimed to systematically...

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Publicado en:Archives of Academic Emergency Medicine Vol. 13; no. 1; pp. 1 - 18
Autores principales: Brock, Roman, Veigl, Christoph, Kornfehl, Andrea, Wittig, Johannes, Heider, Sabine, Tapinova, Karina, Snijders, Erwin, Dunkl, Sabine, Grassmann, Daniel, Heller, Birgit, Krammel, Mario, Schnaubelt, Sebastian
Formato: research systematic review tables/charts Journal Article
Publicado: Shahid Beheshti University of Medical Sciences 2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Chest Compression Synchronized Mechanical Ventilation Modes for Cardiac Arrest; A Scoping Review.
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          Brock, Roman
          Veigl, Christoph
          Kornfehl, Andrea
          Wittig, Johannes
          Heider, Sabine
          Tapinova, Karina
          Snijders, Erwin
          Dunkl, Sabine
          Grassmann, Daniel
          Heller, Birgit
          Krammel, Mario
          Schnaubelt, Sebastian
        affil: Department of Emergency Medicine, Medial University of Vienna, Vienna, Austria.
      sug:
        subj:
          Heart Arrest Therapy
          Respiration, Artificial Methods
          Resuscitation, Cardiopulmonary
          Oxygenation Evaluation
          Hemodynamics Evaluation
          Patient Safety
          Treatment Outcomes
          Human
          Animal Studies
          Scoping Review
          Medline
          Embase
          Blood Gas Analysis
          Intermittent Positive Pressure Ventilation
          Continuous Positive Airway Pressure
          Ventilation, Manual
          Return of Spontaneous Circulation
          Survival Analysis
          Patient Discharge
          Respiration, Artificial Adverse Effects
      ab: Introduction: Chest Compression Synchronized Ventilation (CCSV) is a novel approach aimed at optimizing gas exchange and hemodynamics during cardiopulmonary resuscitation (CPR). However, its clinical value, safety profile and implementation barriers remain unclear. This study aimed to systematically synthesize existing evidence on the use of CCSV during cardiac arrest in animals and humans. Methods: We conducted a scoping review and systematically searched five databases (Medline, Embase, CENTRAL, Scopus, Web of Science) up to May 2025. Studies investigating CCSV or mechanistically related ventilation strategies during cardiac arrest were included regardless of study design, language or publication date. Data were charted for study characteristics, outcomes and adverse events. Results: Thirtytwo studies published between 1980 and 2025 were included. Most were animal studies (n=19), primarily conducted in pigs, with limited human data (n=10). CCSV showed positive effects on arterial oxygenation, carbon dioxide clearance, and hemodynamic parameters as well as cerebral oxygenation compared to conventional ventilation modes. Adverse events such as pneumothorax and lung injury were inconsistently reported. Conclusion: Available data on CCSV suggests potential physiological benefits during CPR, particularly in experimental settings. Human data remain scarce, and larger, prospective human trials are essential to evaluate clinical effectiveness, guide implementation, and assess risks compared to conventional ventilation strategies.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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