Processed Transcript Insertion as a Novel Germline Mutational Mechanism in BRCA1 -Associated Hereditary Breast Cancer.
Simple Summary: Structural variations in cancer predisposition genes significantly contribute to the pool of pathogenic variants underlying heritable cancer susceptibility. In this report, we describe and functionally characterize a novel transposon-mediated germline pathogenic insertion identified...
| Publicado en: | Cancers Vol. 17; no. 23; pp. 3872 - 3883 |
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| Autores principales: | , , , , , , , , |
| Formato: | pictorial tables/charts Journal Article |
| Publicado: |
MDPI
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |