Participant motivation typologies as correlates of study participation and retention in randomized controlled trials targeting cognitive aging through computerized cognitive training.

Background and Objectives Participants' motivations may explain why they participate in Alzheimer's disease and related dementias (ADRD) research. Drawing on the Activator, Motivator, Outside mediator, Re-enforcer (AMOR) model of research engagement, this article utilized a mixed methods design to (...

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Publicado en:Gerontologist Vol. 65; no. 12; pp. 1 - 13
Autores principales: Stephan, Abigail T, Chai, Hye Won, Nicholson, Jody S, McVey, Ava, Phillips, Christine B, Ross, Lesley A
Formato: Artículo
Publicado: Oxford University Press / USA Dec2025
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2025
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      pub: Oxford University Press / USA
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        atl: Participant motivation typologies as correlates of study participation and retention in randomized controlled trials targeting cognitive aging through computerized cognitive training.
      aug:
        au:
          Stephan, Abigail T
          Chai, Hye Won
          Nicholson, Jody S
          McVey, Ava
          Phillips, Christine B
          Ross, Lesley A
        affil: Department of Psychology, Clemson University, Clemson, South Carolina, United StatesInstitute for Engaged Aging, Clemson University, Seneca, South Carolina, United States
      su:
        Human research subjects
        Randomized controlled trials
        Motivation (Psychology)
        Aging
        Medical research
        Cognitive therapy
        Computer assisted instruction
        Cognition
        Patient participation
        Research funding
        Alzheimer's disease
        Statistical sampling
        Logistic regression analysis
        Descriptive statistics
        Chi-squared test
        Thematic analysis
        Research methodology
        Data analysis software
        Dementia
      sug:
        subj:
          Human research subjects
          Randomized controlled trials
          Motivation (Psychology)
          Aging
          Medical research
          Cognitive therapy
          Computer assisted instruction
          Cognition
          Patient participation
          Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
          Marketing Research and Public Opinion Polling
          Research funding
          Alzheimer's disease
          Statistical sampling
          Logistic regression analysis
          Descriptive statistics
          Chi-squared test
          Thematic analysis
          Research methodology
          Data analysis software
          Dementia
      keyword:
        Attrition
        Clinical trial
        Recruitment
        Research participation
        Attrition
        Clinical trial
        Recruitment
        Research participation
      ab: Background and Objectives Participants' motivations may explain why they participate in Alzheimer's disease and related dementias (ADRD) research. Drawing on the Activator, Motivator, Outside mediator, Re-enforcer (AMOR) model of research engagement, this article utilized a mixed methods design to (a) explore participants' reasons for participating and, in some cases, withdrawing from computerized cognitive training studies and (b) connect these reasons to study retention. Research Design and Methods Our convenience sample included community-dwelling adults (N  = 423) between 55 and 88 years (M  = 67.45, SD  = 7.22) from two randomized controlled trials involving computerized cognitive training (Everyday Function Intervention Trial, NCT04651582; Elucidating the Necessary Active Components of Training, NCT05366023). The authors analyzed participants' reasons for participating (shared via written responses) and, when relevant, stated reasons for withdrawing (ascertained via study personnel's notes in participant files) using inductive coding then theoretically informed pattern coding. Associations between reasons for participation and study retention were examined using chi-square tests and logistic regression. Results Primary reasons for participating in research included activating and motivating factors; reasons for withdrawing included outside contextual factors and re-enforcers. Re-enforcers were particularly relevant for withdrawals during the cognitive training phase. Participation reasons were not associated with reasons for, nor likelihood of, withdrawal. Discussion and Implications Findings support an adapted version of the AMOR model for explaining research engagement. Reasons for participating in and withdrawing from trials for computerized cognitive training are nuanced with participants considering multiple factors in their decisions. Applying models of research engagement is critical for identifying and refining recruitment and retention efforts.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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