Artificial Intelligence‐Enabled Short‐Term Ambulatory Monitoring ECG During Sinus Rhythm for Prediction of Hidden Atrial Fibrillation.

Background: Screening of asymptomatic/occult atrial fibrillation (AF) remains challenging. This study aimed to use a deep learning model to predict hidden AF in patients who showed normal sinus rhythm (SR) during 24‐h Holter monitoring. Methods: This was a retrospective cohort study that enrolled 93...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 36; no. 11; pp. 2808 - 2816
Autores principales: Chang, Ting‐Yung, Chen, Song‐Po, Hsieh, Jui‐Hung, Huang, Guan‐Jun, Hung, King‐Chu, Guo, Shu‐Mei, Liu, Chih‐Min, Chang, Shih‐Lin, Lin, Yenn‐Jiang, Lo, Li‐Wei, Hu, Yu‐Feng, Chung, Fa‐Po, Lin, Chin‐Yu, Chen, Shih‐Ann
Formato: research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Nov2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2025
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      pub: Wiley-Blackwell
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        atl: Artificial Intelligence‐Enabled Short‐Term Ambulatory Monitoring ECG During Sinus Rhythm for Prediction of Hidden Atrial Fibrillation.
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        au:
          Chang, Ting‐Yung
          Chen, Song‐Po
          Hsieh, Jui‐Hung
          Huang, Guan‐Jun
          Hung, King‐Chu
          Guo, Shu‐Mei
          Liu, Chih‐Min
          Chang, Shih‐Lin
          Lin, Yenn‐Jiang
          Lo, Li‐Wei
          Hu, Yu‐Feng
          Chung, Fa‐Po
          Lin, Chin‐Yu
          Chen, Shih‐Ann
        affil: Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
      sug:
        subj:
          Electrocardiography, Ambulatory
          Atrial Fibrillation Risk Factors
          Prediction Models
          Deep Learning
          Risk Assessment
          Heart Rate
          Signal Processing, Computer Assisted
          Human
          Retrospective Design
          Record Review
          Prospective Studies
          Long Short-Term Memory
          Sensitivity and Specificity
          Hospitals Taiwan
          Taiwan
          Atrial Fibrillation Diagnosis
          Male
          Female
          Adult
          Middle Age
          Aged
          Comorbidity
          Hypertension
          Coronary Arteriosclerosis
          Diabetes Mellitus
          Renal Insufficiency, Chronic
          Thyroid Diseases
          Stroke
          Pulmonary Disease, Chronic Obstructive
          ROC Curve
          Descriptive Statistics
          Data Analysis Software
          Funding Source
          Atrial Fibrillation Physiopathology
          Predictive Value of Tests
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Screening of asymptomatic/occult atrial fibrillation (AF) remains challenging. This study aimed to use a deep learning model to predict hidden AF in patients who showed normal sinus rhythm (SR) during 24‐h Holter monitoring. Methods: This was a retrospective cohort study that enrolled 934 patients receiving 24‐h ambulatory Holter monitoring. Of them, 640 patients (AF group) had the documented paroxysmal AF in the index Holter monitoring. The rest of 294 patients (Control group) did not have medical record of AF and the index Holter exam did not detect AF. A ConvNeXt model (1st stage) and Long Short‐Term Memory (LSTM) (2nd stage) was used to predict the probability of AF. Results: 368,550 eligible SR ECG segments (60 s/segment) were taken into 1st staged classification, and the Area Under Curve (AUC) was 0.7755 with accuracy of 0.7755, sensitivity of 0.9105, and specificity of 0.5718. After 2nd staged classification (10‐min SR ECG recording), the AUC reached 0.874 (accuracy of 0.8213, sensitivity of 0.8339, and specificity of 0.8115). The fact that longer time length examined in the 2nd stage leaded to a dilution of features more related to AF might decrease specificity compared with 1st stage. Subgroup analysis demonstrated that night‐time settings had better performance (AUC: 0.902 in night‐time, 0.8726 in day‐time). Conclusion: We developed an AI‐enabled model with 10 min ECG recording from ambulatory Holter monitoring during SR to predict hidden AF with high accuracy. Subgroup analysis according to the diurnal period, night‐time settings showed more favorable performance compared to day‐time recordings.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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