Respiratory-Swallowing Phase Pattern and Swallowing Impairment in Individuals With Parkinson's Disease.
Purpose: Swallowing and respiratory impairments in Parkinson's disease (PD) may contribute to atypical respiratory-swallowing phase patterning. This exploratory study aimed to (a) quantify swallowing impairment and airway protection, (b) determine respiratory-swallowing phase pattern at swallow init...
| Publicado en: | Journal of Speech, Language & Hearing Research Vol. 69; no. 1; pp. 32 - 46 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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American Speech-Language-Hearing Association
Jan2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=190839083&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 190839083 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Jan2026 vid: 69 iid: 1 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 190839083 10.1044/2025_JSLHR-25-00135 ppf: 32 ppct: 14 formats: fmt: @attributes: type: P size: 924KB tig: atl: Respiratory-Swallowing Phase Pattern and Swallowing Impairment in Individuals With Parkinson's Disease. aug: au: Rangwala, Rabab Davidson, Kate Lee, Jungwha Garand, Kendrea L. (Focht) Bega, Danny Martin-Harris, Bonnie affil: Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, IL Department of Otolaryngology--Head and Neck Surgery, Medical University of South Carolina, Charleston Department of Preventive Medicine (Biostatistics & Informatics), Feinberg School of Medicine, Northwestern University, Chicago, IL Department of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL Otolaryngology--Head and Neck Surgery, Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL su: Research funding Respiration Parkinson's disease Descriptive statistics Odds ratio Deglutition Data analysis software Comparative studies Confidence intervals Deglutition disorders sug: subj: Research funding Respiration Parkinson's disease Descriptive statistics Odds ratio Deglutition Data analysis software Comparative studies Confidence intervals Deglutition disorders ab: Purpose: Swallowing and respiratory impairments in Parkinson's disease (PD) may contribute to atypical respiratory-swallowing phase patterning. This exploratory study aimed to (a) quantify swallowing impairment and airway protection, (b) determine respiratory-swallowing phase pattern at swallow initiation, and (c) test the association between swallowing impairment, airway protection, and respiratory-swallowing phase pattern in PD. Method: A total of 31 adults with PD and dysphagia underwent simultaneous videofluoroscopy and respiratory inductance plethysmography following the Modified Barium Swallow Impairment Profile (MBSImP) protocol. Endpoints included MBSImP swallow-by-swallow (SS) and overall impression (OI) scores, Penetration-Aspiration Scale (PAS) scores, and respiratory-swallowing phase pattern at swallow initiation. Historical data from 84 healthy controls aged 40 years and above were used for MBSImP and PAS comparisons. Logistic regression models with random effects assessed impact of patient group on MBSImP, PAS, and respiratory-swallowing phase patterns, and the associations between MBSImP, PAS, and respiratory-swallowing phase patterns. Results: PD demonstrated significantly increased odds for higher (worse) OI scores on lip closure (p = .0002), tongue control (p < .0001), bolus preparation/mastication (p = .016), oral residue (p = .036), laryngeal elevation (p = .001), laryngeal vestibular closure (p = .001), esophageal clearance (p = .011), and higher maximum PAS scores (p = .017). Additionally, swallowing was initiated during inspiration on 26% of trials and was associated with higher odds of impairment in initiation of pharyngeal swallow (p = .038), laryngeal vestibular closure (p = .026), tongue base retraction (p = .013), and PAS scores (p = .017). Conclusions: PD patients demonstrated greater frequency of swallows initiated during inspiration with higher MBSImP and maximum PAS scores relative to healthy controls. Replication of these findings in large, homogenous PD samples may clarify the relevance for retraining typical respiratory-swallowing phase patterning benefiting swallowing improvement. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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