Frequency-Following Response in Infants With Congenital Syphilis.
Purpose: This work aimed to study the frequency-following response (FFR) of infants with congenital syphilis under treatment. Method: A cross-sectional study with 112 infants recruited at public maternities was conducted. A total of 90 infants were included in the sample and divided into two groups:...
| Publicado en: | Journal of Speech, Language & Hearing Research Vol. 69; no. 1; pp. 320 - 333 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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American Speech-Language-Hearing Association
Jan2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=190839099&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 190839099 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Jan2026 vid: 69 iid: 1 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 190839099 10.1044/2025_JSLHR-24-00179 ppf: 320 ppct: 13 formats: fmt: @attributes: type: P size: 1.1MB tig: atl: Frequency-Following Response in Infants With Congenital Syphilis. aug: au: Balen, Sheila Andreoli de Souza Evangelista, Carolina Karla Ribas-Prats, Teresa Santos, Ana Beatriz Arenillas-Alcón, Sonia Escera, Carles affil: Undergraduate Program in Speech, Language and Hearing Sciences, Federal University of Rio Grande do Norte, Natal, Brazil Laboratory of Technological Innovation in Health (LAIS), Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil Graduate Associate Program in Speech, Language and Hearing Sciences, Federal University of Rio Grande do Norte, Natal, Brazil Leibniz Institute for Neurobiology, 39118, Magdeburg, Germany Institute of Neurosciences, University of Barcelona, Spain Institute de Recerca Sant Joan de Deu (IRSJD), Barcelona, Spain BrainLab-Cognitive Neuroscience Research Group, Department of Clinical Psychology and Psychobiology, University of Barcelona, Spain su: Brazil Cross-sectional method Mother-infant relationship Psychology of mothers Hearing Language acquisition Disease risk factors Brain stem physiology Diagnosis of HIV infections Risk assessment Research funding Congenital, hereditary, & infantile syphilis Neural pathways Coronary circulation Treatment effectiveness Descriptive statistics Pediatrics Speech perception Acoustic stimulation Comparative studies Hearing disorders Auditory evoked response Sensitivity & specificity (Statistics) Disease progression sug: subj: Cross-sectional method Mother-infant relationship Psychology of mothers Hearing Language acquisition Disease risk factors Brazil Brain stem physiology Diagnosis of HIV infections Risk assessment Research funding Congenital, hereditary, & infantile syphilis Neural pathways Coronary circulation Treatment effectiveness Descriptive statistics Pediatrics Speech perception Acoustic stimulation Comparative studies Hearing disorders Auditory evoked response Sensitivity & specificity (Statistics) Disease progression ab: Purpose: This work aimed to study the frequency-following response (FFR) of infants with congenital syphilis under treatment. Method: A cross-sectional study with 112 infants recruited at public maternities was conducted. A total of 90 infants were included in the sample and divided into two groups: 53 infants whose mothers and infants received perinatal syphilis treatment and 37 infants whose mothers and infants were free of syphilis (control group). Infant age ranged from 15 to 90 days (M = 39.9 ± 17.2 days). FFRs were recorded to a 170-ms consonant-vowel /da/stimulus, presented at 80 dB nHL to the right ear. Data were analyzed in the time and frequency domains. The Shapiro-Wilk and Mann-Whitney U tests were applied with a significance level of p = .05. Results: No significant between-groups differences were observed in FFR spectral amplitude at the stimulus fundamental frequency or its harmonics, whether computed in the transient or steady portions of the stimulus. No significant differences were observed in prestimulus root-mean-square, neural lag, and the signal-to-noise ratio of the spectral amplitude. Conclusion: These findings suggest that infants with congenital syphilis, when appropriately treated at birth, demonstrate preserved auditory pathway function and sound processing, including temporal and spectral characteristics that are relevant for language acquisition. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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