Longitudinal patterns of loss of independence in Parkinson disease.
Aim: To examine the longitudinal loss of independence (LOI) in Parkinson disease (PD) and introduce event visualization as a research tool. Methods: Early-stage PD patients seen by a movement disorders specialist from 2003–2020 were included. LOI, defined as needing help with activities of daily liv...
| Published in: | Neurodegenerative Disease Management Vol. 16; no. 1; pp. 1 - 12 |
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| Main Authors: | , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Feb2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190930928&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190930928 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17582024 B9ZV jtl: Neurodegenerative Disease Management issn: 17582024 maglogo: N pubinfo: dt: Feb2026 vid: 16 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 190930928 190930928 190930928 10.1080/17582024.2025.2514982 190930928 ppf: 1 ppct: 11 formats: tig: atl: Longitudinal patterns of loss of independence in Parkinson disease. aug: au: Lee, Tsung-Ying Shulman, Lisa M. Gruber-Baldini, Ann L. Slejko, Julia F. Gopalakrishnan, Mathangi Onukwugha, Eberechukwu affil: Department of Practice, Sciences, and Health Outcomes Research, University of Maryland School of Pharmacy, Baltimore, MD, USA sug: subj: Parkinson Disease Psychosocial Factors Parkinson Disease Physiopathology Activities of Daily Living Disease Progression Guided Imagery Human Maryland Male Female Adult Middle Age Aged Prospective Studies Scales Questionnaires Descriptive Statistics Patient-Reported Outcomes Functional Status Support, Social Counseling Disability Evaluation Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Aim: To examine the longitudinal loss of independence (LOI) in Parkinson disease (PD) and introduce event visualization as a research tool. Methods: Early-stage PD patients seen by a movement disorders specialist from 2003–2020 were included. LOI, defined as needing help with activities of daily living (ADLs), was assessed using the modified Older Americans Resources and Services Daily Function Questionnaire. EventFlow software visualized LOI patterns. Results: The cohort included 296 patients (mean age 60.8; 61% male; 94% Hoehn & Yahr stages 1–2). At baseline, 91% were independent. LOI occurred in 133 patients for ≥ 1 ADL, and in 95 patients for ≥ 3 ADLs. Housework was the most frequent first ADL needing help (58 of 133), with a mean onset of 4.6 years. Among those with LOI, 57 (43%) regained independence at least once. Conclusion: LOI in PD shows both transient and persistent patterns. Event visualization may aid understanding of progression and support patient counseling. Plain Language Summary: People with Parkinson disease (PD) often worry about losing their ability to do everyday tasks on their own. In this study, we followed nearly 300 individuals with early-stage PD over several years to understand how their independence changed over time. We looked at when they first began needing help with daily activities, such as preparing meals, shopping, or housework. During the study, we found that almost half of the patients reported needing help with at least one task – most often housework. However, many of them later regained their independence, sometimes more than once. Our findings suggest that some people improve after their independence loss, possibly with treatments or supports. This information may help people living with PD – and their families – better understand what to expect and how to prepare for the future. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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