Warm Autoimmune Hemolytic Anemia Comorbidity and COVID-19 Infection: A Case Report.

Apart from severe acute respiratory syndrome and cytokine dysregulation, novel coronavirus disease 2019 (COVID-19) infection has also been associated with a broad range of complications including septicemia, thrombosis, thrombocytopenia, Guillain--Barre, antiphospholipid syndrome, and multiple organ...

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Publicado en:Clinical Laboratory Science Vol. 37; no. 1; pp. 12 - 18
Autores principales: GOMEZ, ISRAEL, TURKEL, SARAH, NASR, PAYMAN
Formato: case study tables/charts Journal Article
Publicado: American Society for Clinical Laboratory Science Winter2024
Acceso en línea:Ver este registro en EBSCOhost
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    uiTerm: 190973708
    longDbName: CINAHL Complete
    uiTag: AN
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      jtl: Clinical Laboratory Science
      issn: 0894959X
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    pubinfo:
      dt: Winter2024
      vid: 37
      iid: 1
      pid: 13703
      pub: American Society for Clinical Laboratory Science
      place: Dundee, Michigan
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        atl: Warm Autoimmune Hemolytic Anemia Comorbidity and COVID-19 Infection: A Case Report.
      aug:
        au:
          GOMEZ, ISRAEL
          TURKEL, SARAH
          NASR, PAYMAN
        affil: California State University, Dominguez Hills
      sug:
        subj:
          Anemia, Hemolytic, Autoimmune Diagnosis
          Anemia, Hemolytic, Autoimmune Therapy
          Comorbidity
          COVID-19
          Male
          Adult
          Glucocorticoids
          Physical Examination
          Abdomen Ultrasonography
          Hepatomegaly
          Splenomegaly
          Diagnosis, Laboratory
          Prednisone Administration and Dosage
          Dexamethasone
          Rituximab
          Hemoglobins
          Adult: 19-44 years
          Male
      ab: Apart from severe acute respiratory syndrome and cytokine dysregulation, novel coronavirus disease 2019 (COVID-19) infection has also been associated with a broad range of complications including septicemia, thrombosis, thrombocytopenia, Guillain--Barre, antiphospholipid syndrome, and multiple organ failure. Warm autoimmune hemolytic anemia (WAIHA) in its clinical presentation is similar to other forms of hemolytic anemias in which hemoglobin level is the most direct indicator of clinical severity of the hemolytic event. In this report, we describe the case of a 31-year-old male, previously diagnosed with idiopathic WAIHA, who goes on to suffer a severe flare following a COVID-19 infection. Prior to the COVID-19 infection, the patient was in a stable condition and was taking part in a clinical study for the treatment of WAIHA. In the case of this patient, the COVID-19 infection elicited a severe hemolytic episode, which required admission to the hospital and multiple units of blood transfusion. The patient's hematological recovery correlated with improvement from COVID-19 symptoms. The patient was stabilized with glucocorticoids and discharged after 2 weeks of hospitalization. The current case supports the role of COVID-19 infection as a comorbidity factor in WAIHA.
      pubtype: Academic Journal
      doctype:
        case study
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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