PrEP Use Likelihood Among People Who Use Opioid Drugs: Understanding Clinical Correlates Along the Opioid Use Disorder Treatment Cascade.
People with opioid use disorder (PWOUD) are at high risk of HIV infection, yet uptake of PrEP remains low in PWOUD. To understand opportunities to increase PrEP engagement, this cross-sectional study sought to examine clinical correlates of perceived PrEP use likelihood in a sample of PWOUD along th...
| Publicado en: | AIDS & Behavior Vol. 30; no. 1; pp. 179 - 190 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jan2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=190984211&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 190984211 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Jan2026 vid: 30 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 190984211 187378898 190984211 190984211 10.1007/s10461-025-04857-x 190984211 ppf: 179 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: PrEP Use Likelihood Among People Who Use Opioid Drugs: Understanding Clinical Correlates Along the Opioid Use Disorder Treatment Cascade. aug: au: Sullivan, Matthew C. Davis, Madison J. O'Cleirigh, Conall Batchelder, Abigail W. affil: https://ror.org/002pd6e78 Behavioral Medicine Service, Massachusetts General Hospital, Boston, MA, USA sug: subj: Pre-Exposure Prophylaxis Psychosocial Factors Persons with Substance Use Disorders Psychosocial Factors Analgesics, Opioid Adverse Effects Substance Use Disorders Drug Therapy Patient Attitudes Evaluation HIV Infections Prevention and Control Human Administration, Oral Injections Emotions Patient Preference Drug Utilization Emergency Service Correlational Studies Sexual Partners Social Networks HIV Infections Risk Factors Needle Sharing Probability Purposive Sample Adolescence Adult Middle Age Aged Cross Sectional Studies Surveys Questionnaires Descriptive Statistics T-Tests Chi Square Test Fisher's Exact Test Logistic Regression Male Female Odds Ratio Confidence Intervals Bivariate Statistics Pearson's Correlation Coefficient Data Analysis Software Funding Source Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: People with opioid use disorder (PWOUD) are at high risk of HIV infection, yet uptake of PrEP remains low in PWOUD. To understand opportunities to increase PrEP engagement, this cross-sectional study sought to examine clinical correlates of perceived PrEP use likelihood in a sample of PWOUD along the OUD Treatment Cascade. We enrolled 120 PWOUD with past-6-month injection drug use (IDU) or condomless sex in a cross-sectional survey study. Participants were recruited from sites serving PWOUD in the Boston area, including substance use disorder (SUD) treatment programs and harm reduction service providers. PWOUD characterized their substance use and treatment history, perceived risk of acquiring HIV, and likelihood of using oral and long-acting injectable (LAI) PrEP. Ordinal logistic regression and Pearson correlations were used to examine correlates of likelihood of using oral and LAI-PrEP. Contrary to hypotheses, current MOUD engagement was not associated with perceived likelihood of using oral or LAI-PrEP. More recent IDU was associated with greater likelihood of using both oral PrEP (OR = 0.98, 95% CI: 0.97, 0.99) and LAI-PrEP (OR = 0.99, 95% CI: 0.98, 1.00). PWOUD who received past-year emergency department-based SUD treatment endorsed lower likelihood of using LAI-PrEP (OR = 0.40, 95% CI: 0.19, 0.84). Among PWOUD, a greater number of sex partners was a stronger correlate of perceived risk of acquiring HIV than IDU-related risk behaviors. Results suggest opportunities to engage PWOUD at greatest HIV risk in PrEP care; findings also suggest need for education interventions to inform judgments of HIV risk among PWOUD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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