An Electronic Health Record Algorithm's Performance to Identify Cognitive Impairment in Primary Care.

Most people with dementia are diagnosed and cared for in primary care. We examined the performance of an electronic health record (EHR) algorithm to identify older adults with dementia or mild cognitive impairment in primary care. Retrospective cohort study. We identified all adults aged 65+ seen fo...

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Publicado en:Journal of the American Medical Directors Association Vol. 27; no. 1
Autores principales: Kistler, Christine E., Lynch, Molly E., Lin, Feng-Chang, Yang, Yumei, Frazier, Winfred, Hanson, Laura C.
Formato: research Journal Article
Publicado: Elsevier B.V. Jan2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2026
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        atl: An Electronic Health Record Algorithm's Performance to Identify Cognitive Impairment in Primary Care.
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        au:
          Kistler, Christine E.
          Lynch, Molly E.
          Lin, Feng-Chang
          Yang, Yumei
          Frazier, Winfred
          Hanson, Laura C.
        affil: Division of Geriatric Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
      sug:
        subj:
          Dementia Diagnosis
          Mild Cognitive Impairment Diagnosis
          Electronic Health Records
          Algorithms Evaluation
          Primary Health Care
          Human
          Aged
          Aged, 80 and Over
          Male
          Female
          Retrospective Design
          Record Review
          Prospective Studies
          International Classification of Diseases
          Coding
          Descriptive Statistics
          White Persons
          Sensitivity and Specificity
          Predictive Value of Tests
          Diagnosis, Computer Assisted
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Most people with dementia are diagnosed and cared for in primary care. We examined the performance of an electronic health record (EHR) algorithm to identify older adults with dementia or mild cognitive impairment in primary care. Retrospective cohort study. We identified all adults aged 65+ seen for a routine visit from December 2021 to December 2022 in 59 primary care clinics. We used representative sampling to create a cohort of 525 older adults. We used trained research staff to confirm the presence of dementia or mild cognitive impairment via gold standard chart review. We then applied a list of 114 cognitive impairment–related Internaitonal Classification of Diseases, 10th Revision (ICD-10) codes and prescribed dementia medications to the cohort and evaluated the algorithm's performance characteristics. Of the representative cohort (n = 525), 59% were women and 81% were White, with an average age of 74.5 ± 6.9 years. Dementia or mild cognitive impairment was present on EHR review in 8.6% (n = 45) of the cohort. The algorithm had a specificity of 98.1%, a sensitivity of 60.0%, a positive predictive value of 0.75, and a negative predictive value of 0.96. The overall predictive performance (F-1 score) was 0.667. Nonspecific ICD-10 was the most common, with "unspecified dementia" representing 17 of 34 ICD-10 codes found by the algorithm. Optimization of an EHR algorithm to detect cognitive impairment by combining cognitive impairment–related ICD-10 codes and dementia medications identified people with dementia or mild cognitive impairment in primary care with high specificity and acceptable sensitivity, although ICD-10 codes remained nonspecific.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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