Clinical Pharmacology Characterization of the First‐In‐Class Oncolytic Viral Therapy T‐VEC in Adults and Pediatric Subjects.

Oncolytic viruses are an emerging class of immunotherapies for cancer treatment. Talimogene laherparepvec (T‐VEC) is a first‐in‐class oncolytic virus approved globally for advanced melanoma. Herein, we describe the quantitative clinical pharmacology aspects of T‐VEC that supported the development of...

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Bibliographic Details
Published in:Journal of Clinical Pharmacology Vol. 66; no. 1; pp. 1 - 14
Main Authors: Zhang, Xinwen, Balu, Bhavya, Chen, Po‐Wei, Mehta, Khamir, Li, Chuang, Upreti, Vijay V.
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Jan2026
Online Access:View this record in EBSCOhost