Effect of Acupuncture on Anxiety, Depression, and Quality of Life in Patients with Irritable Bowel Syndrome: A Meta-Analysis.

Background: Irritable bowel syndrome (IBS) has been effectively treated with acupuncture, but the significance of quality of life, depression, and anxiety in the assessment of IBS patients has received little consideration. This study examined the impact of acupuncture on depression, anxiety, and qu...

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Publicado en:International Journal of Behavioral Medicine Vol. 32; no. 6; pp. 834 - 855
Autores principales: Fang, Xue, Wang, XiaoYan, Zheng, WenJun, Yin, Ying, Ge, XiaoBin
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Effect of Acupuncture on Anxiety, Depression, and Quality of Life in Patients with Irritable Bowel Syndrome: A Meta-Analysis.
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          Fang, Xue
          Wang, XiaoYan
          Zheng, WenJun
          Yin, Ying
          Ge, XiaoBin
        affil: https://ror.org/052q26725 Affiliated Hospital of Shandong University of Traditional Chinese Medicine, 250011, Jinan, Shandong Province, China
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        subj:
          Acupuncture
          Anxiety Therapy
          Depression Therapy
          Quality of Life
          Irritable Bowel Syndrome
          Treatment Outcomes
          Human
          Systematic Review
          Meta Analysis
          Cochrane Library
          Embase
          PubMed
          Adverse Health Care Event Risk Factors
          Treatment Duration
          Checklists
          Data Analysis Software
          Funding Source
      ab: Background: Irritable bowel syndrome (IBS) has been effectively treated with acupuncture, but the significance of quality of life, depression, and anxiety in the assessment of IBS patients has received little consideration. This study examined the impact of acupuncture on depression, anxiety, and quality of life in IBS patients. Method: PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), EMBASE, China Science and Technology Journal Database (VIP), Chinese Biological Medical (CBM, SinoMed) Database, and the Wan Fang Database were among the electronic databases from which relevant randomized controlled trials (RCTs) were systematically retrieved between their inception and July 2023. The outcomes included adverse events, total response rate, anxiety, and symptoms of depression, as well as quality of life. In this study, the heterogeneity, publication bias, standardized mean difference (SMD), and risk ratios (RR) with 95% confidence intervals (CI) were estimated. Results: In this study, 29 RCTs including 3114 participants for analysis (treatment group, 1730; control group, 1384) were included. Compared to other therapies, acupuncture significantly improved the quality of life (SMD = 0.61, 95% CI = [0.26, 0.96], P < 0.001) and alleviated anxiety (SMD = − 0.72, 95% CI = [− 1.76, 0.32], P = 0.18) and depression (SMD = − 0.74, 95% CI = [− 1.18, − 0.3], P < 0.001) in IBS patients. A statistically significant improvement was recorded in their quality of life, and they also displayed fewer symptoms of depression. The total response rate (RR = 1.18, 95% CI = [1.12, 1.25], P < 0.001) indicated that acupuncture significantly affected IBS treatment in comparison to other methods. Subgroup analysis of primary outcome indicators revealed that acupuncture demonstrated better results regardless of the duration of intervention and was more effective than Western medicine or sham acupuncture. In addition to the total response rate (I2 = 0%), the other three outcome indicators showed significant heterogeneity (I2 > 50%). No publication bias was noted in RR (P < 0.05); however, a significant publication bias was observed in quality of life (P > 0.05). Conclusion: Acupuncture can enhance the quality of life and relieve anxiety and depression in patients with IBS with apparent safety; however, a large number of high-quality RCTs are still needed.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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