From bench to bedside, blade, and back: FAP expression in juvenile angiofibroma. Potential implications for FAPI-PET/CT imaging and targeted therapy?

Purpose: Juvenile angiofibroma (JA) is a rare, benign fibrovascular tumor that predominantly affects adolescent males. The underlying biological mechanisms remain poorly understood. Fibroblast activation protein (FAP), known for its involvement in tumor invasion, matrix remodeling, and angiogenesis,...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine & Molecular Imaging Vol. 53; no. 2; pp. 753 - 763
Main Authors: Pillong, Lukas, Burgard, Caroline, Rosar, Florian, Demirkol, Betül, Ebner, Rafail, Linxweiler, Maximilian, Bozzato, Alessandro, Schick, Bernhard, Wemmert, Silke
Format: Journal Article
Published: Springer Nature Jan2026
Online Access:View this record in EBSCOhost