Predictors of Social Frailty and Depression in Brazilian Patients With Chronic Kidney Disease: A Cross‐Sectional Study.

Background: Social frailty is linked to adverse health outcomes, including depression, especially in older and chronically ill individuals. This study aimed to assess the prevalence and associated factors of social frailty in Brazilian CKD patients undergoing hemodialysis or kidney transplantation a...

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Publicado en:Geriatrics & Gerontology International Vol. 26; no. 1; pp. 1 - 8
Autores principales: dos Santos, Diana Gabriela Mendes, Geraigire, Luma, Ferreira, Layana Giselly Silva, Costa da Silva, Cleanderson, de Souza Dinardi, Ana Carolina, Zazzetta, Marisa Silvana, de Souza Orlandi, Fabiana
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jan2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2026
      vid: 26
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        191138408
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        10.1111/ggi.70317
        191138408
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        atl: Predictors of Social Frailty and Depression in Brazilian Patients With Chronic Kidney Disease: A Cross‐Sectional Study.
      aug:
        au:
          dos Santos, Diana Gabriela Mendes
          Geraigire, Luma
          Ferreira, Layana Giselly Silva
          Costa da Silva, Cleanderson
          de Souza Dinardi, Ana Carolina
          Zazzetta, Marisa Silvana
          de Souza Orlandi, Fabiana
        affil: Department of Nursing, Federal University of São Carlos, São Carlos, Brazil
      sug:
        subj:
          Social Isolation Epidemiology
          Depression Risk Factors
          Renal Insufficiency, Chronic Therapy
          Brazilians
          Hemodialysis
          Dialysis Patients
          Kidney Transplantation
          Transplant Recipients
          Risk Assessment
          Support, Social
          Interpersonal Relations
          Frailty Syndrome Risk Factors
          Frailty Syndrome Epidemiology
          Human
          Cross Sectional Studies
          Correlational Studies
          Comparative Studies
          Brazil
          Loneliness
          Poverty
          Educational Status
          Sociodemographic Factors
          Convenience Sample
          Questionnaires
          Descriptive Statistics
          Mann-Whitney U Test
          Chi Square Test
          Multiple Linear Regression
          Data Analysis Software
          Adult
          Middle Age
          Aged
          Male
          Female
          Support, Psychosocial
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Social frailty is linked to adverse health outcomes, including depression, especially in older and chronically ill individuals. This study aimed to assess the prevalence and associated factors of social frailty in Brazilian CKD patients undergoing hemodialysis or kidney transplantation and to examine its predictive role in the development of depressive symptoms. Methods: This cross‐sectional, correlational, and comparative study included 284 patients with CKD from São Paulo, Brazil. Data were collected using validated instruments: HALFT Social Frailty Scale, Patient Health Questionnaire‐9 (PHQ‐9), and Medical Outcomes Study Social Support Scale (MOS). Two multiple linear regression (MLR) models were used to assess predictors of social frailty and depressive symptoms, adjusting for sociodemographic and clinical variables. Results: Social frailty was significantly more prevalent among HD patients (51.2%) compared to TX patients (24%). Social support was negatively associated with social frailty (β = −0.40; p < 0.001). Other predictors of greater social frailty included lower income (β = 0.51 for ≤ 1 minimum wage), number of medications (β = 0.11), and lower education (β = −0.13). In turn, social frailty was the strongest predictor of depressive symptoms (β = 0.60; p < 0.001). TX status and male sex were associated with lower depression scores. Conclusion: Social frailty is highly prevalent in CKD patients, particularly those undergoing HD, and strongly predicts depressive symptoms. Strategies to enhance social support and reduce socioeconomic vulnerability may help mitigate mental health burdens in this population.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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