Efficacy of a large language model in classifying branch-duct intraductal papillary mucinous neoplasms.

Objectives: Appropriate categorization based on magnetic resonance imaging (MRI) findings is important for managing intraductal papillary mucinous neoplasms (IPMNs). In this study, a large language model (LLM) that classifies IPMNs based on MRI findings was developed, and its performance was compare...

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Publicado en:Abdominal Radiology Vol. 51; no. 1; pp. 417 - 424
Autores principales: Sato, Mai, Yasaka, Koichiro, Abe, Shimon, Kurashima, Joji, Asari, Yusuke, Kiryu, Shigeru, Abe, Osamu
Formato: Journal Article
Publicado: Springer Nature Jan2026
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Efficacy of a large language model in classifying branch-duct intraductal papillary mucinous neoplasms.
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          Sato, Mai
          Yasaka, Koichiro
          Abe, Shimon
          Kurashima, Joji
          Asari, Yusuke
          Kiryu, Shigeru
          Abe, Osamu
        affil: https://ror.org/057zh3y96 The University of Tokyo, Tokyo, Japan
      sug:
      ab: Objectives: Appropriate categorization based on magnetic resonance imaging (MRI) findings is important for managing intraductal papillary mucinous neoplasms (IPMNs). In this study, a large language model (LLM) that classifies IPMNs based on MRI findings was developed, and its performance was compared with that of less experienced human readers. Methods: The medical image management and processing systems of our hospital were searched to identify MRI reports of branch-duct IPMNs (BD-IPMNs). They were assigned to the training, validation, and testing datasets in chronological order. The model was trained on the training dataset, and the best-performing model on the validation dataset was evaluated on the test dataset. Furthermore, two radiology residents (Readers 1 and 2) and an intern (Reader 3) manually sorted the reports in the test dataset. The accuracy, sensitivity, and time required for categorizing were compared between the model and readers. Results: The accuracy of the fine-tuned LLM for the test dataset was 0.966, which was comparable to that of Readers 1 and 2 (0.931–0.972) and significantly better than that of Reader 3 (0.907). The fine-tuned LLM had an area under the receiver operating characteristic curve of 0.982 for the classification of cyst diameter ≥ 10 mm, which was significantly superior to that of Reader 3 (0.944). Furthermore, the fine-tuned LLM (25 s) completed the test dataset faster than the readers (1,887–2,646 s). Conclusion: The fine-tuned LLM classified BD-IPMNs based on MRI findings with comparable performance to that of radiology residents and significantly reduced the time required.
      pubtype: Academic Journal
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    language: English
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