| Sumario: | Background: A significant shortage of available organs for transplantation persists globally, with insufficient education on organ donation recognized as a key contributing factor. Allied health students, when equipped with accurate knowledge, have the potential to serve as advocates for organ donation, influencing public attitudes through their social networks. Enhancing their understanding may contribute to increased organ donation awareness and acceptance within the broader community. Methods: This study employed a quasi-experimental design to examine the effect of an educational intervention program on allied health students' knowledge and attitudes toward organ donation and transplantation. A total of 150 allied health students were recruited through simple random sampling. Data were collected using a valid and reliable translated self-administered online questionnaire. Participants were divided into intervention and control groups. Descriptive statistics, independent sample t-tests, and one-way ANOVA were used for data analysis. Results: Following the intervention, the mean score of knowledge and attitudes in the intervention group (M = 41.09, SD = 2.57) was significantly higher than that in the control group (M = 40.29, SD = 2.40), with a t-value of −3.49 and a p-value of <0.001. These results indicate that the educational program had a statistically significant positive effect on participants' knowledge and attitudes regarding organ donation and transplantation. Conclusions: The implementation of the educational intervention significantly improved allied health students' knowledge and attitudes toward organ donation and transplantation. This suggests that targeted educational programs for future health professionals may be an effective strategy to promote organ donation awareness and address the shortage of organ donors.
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