Factors Associated with Nutritional Risk in Colorectal Cancer Patients Undergoing Chemotherapy: A Secondary Analysis of a Cross-Sectional Study.

Background/Objectives: Our previous study showed that the dietary structure is imbalanced in a majority of colorectal cancer patients receiving chemotherapy. These patients had higher risk of developing malnutrition. In the present study, we aimed to identify factors associated with nutritional risk...

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Publicado en:Nursing Reports Vol. 16; no. 1; pp. 27 - 41
Autores principales: Xu, Yan, Du, Qianqian, Luo, Ningxiang, Lai, Shurong, Zhou, Zhijun, Zhang, Meifen
Formato: research tables/charts Journal Article
Publicado: MDPI Jan2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2026
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      pub: MDPI
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        atl: Factors Associated with Nutritional Risk in Colorectal Cancer Patients Undergoing Chemotherapy: A Secondary Analysis of a Cross-Sectional Study.
      aug:
        au:
          Xu, Yan
          Du, Qianqian
          Luo, Ningxiang
          Lai, Shurong
          Zhou, Zhijun
          Zhang, Meifen
        affil: Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510000, China
      sug:
        subj:
          Malnutrition Risk Factors
          Risk Assessment
          Colorectal Neoplasms Drug Therapy
          Chemotherapy, Cancer
          Human
          Secondary Analysis
          Diet Evaluation
          Severity of Illness
          Nutritional Status
          Age Factors
          Univariate Statistics
          Body Mass Index
          Health Knowledge
          Food Intake
          Surgery, Operative
          Odds Ratio
          Confidence Intervals
          Chemotherapy, Cancer Classification
          Postoperative Complications
          Data Analysis Software
          Descriptive Statistics
          Pearson's Correlation Coefficient
          Spearman's Rank Correlation Coefficient
          Chi Square Test
          T-Tests
          Logistic Regression
          Multivariate Analysis
          Clinical Assessment Tools
          Questionnaires
          Funding Source
      ab: Background/Objectives: Our previous study showed that the dietary structure is imbalanced in a majority of colorectal cancer patients receiving chemotherapy. These patients had higher risk of developing malnutrition. In the present study, we aimed to identify factors associated with nutritional risk in this cohort of patients. Methods: We performed a secondary analysis of a dataset that was originally collected to identify the factors that are associated with an imbalanced dietary structure in patients receiving chemotherapy for colorectal cancer. Nutritional risk was evaluated by using an NRS-2002 form. Binary logistic regression was used for multivariate analysis. Results: Among the 178 CRC patients enrolled in this study, 60 (33.7%) had nutritional risk. Patients with nutritional risk exhibited lower intake of grains, potatoes, vegetables, fruits, beans, nuts, and oils compared to those without risk. Multivariate analysis showed that non-surgery (95% CI: 0.130–0.914, p = 0.032) and high dietary structure score (95% CI: 0.808–0.944, p = 0.001) are associated with lower nutritional risk in CRC patients receiving chemotherapy. Conclusions: CRC patients receiving chemotherapy have moderate risk of developing malnutrition. Dietary structure score and surgery are associated with malnutrition in CRC patients receiving chemotherapy. Education on proper dietary structure is a potential strategy to mitigate nutritional risk in CRC patients undergoing chemotherapy. These findings highlight the need for personalized nutritional support to optimize patient outcomes.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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