Sex Differences in Autistic Youth Born Extremely Preterm.
Purpose: To evaluate sex differences in autistic traits in youth born extremely preterm (EP; 23–27 weeks) who were later diagnosed with autism spectrum disorder (ASD) at 10-years. Method: A longitudinal cohort design from the Extremely Low Gestational Age Newborn Study (ELGAN) followed N = 857 EP in...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 56; no. 2; pp. 830 - 838 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Feb2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191290367&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191290367 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Feb2026 vid: 56 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 191290367 176031454 191290367 191290367 10.1007/s10803-024-06319-0 191290367 ppf: 830 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Sex Differences in Autistic Youth Born Extremely Preterm. aug: au: McFayden, Tyler C. Harrop, Clare Roell, Kyle Joseph, Robert M. Fry, Rebecca C. O'Shea, T. Michael affil: https://ror.org/0130frc33 Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA sug: subj: Autism Spectrum Disorder Diagnosis Sex Factors Evaluation Infant, Premature Human Funding Source Male Female Nonexperimental Studies Prospective Studies United States Infant, Newborn Infant Child, Preschool Child Probability Scales Checklists Interview Guides Questionnaires T-Tests Wilcoxon Signed Rank Test Fisher's Exact Test Descriptive Statistics Data Analysis Software Communication Adolescence Infant, Newborn: birth-1 month Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years Male Female ab: Purpose: To evaluate sex differences in autistic traits in youth born extremely preterm (EP; 23–27 weeks) who were later diagnosed with autism spectrum disorder (ASD) at 10-years. Method: A longitudinal cohort design from the Extremely Low Gestational Age Newborn Study (ELGAN) followed N = 857 EP infants from birth through 10-years. EP infants later diagnosed with ASD (N = 61, 20 females) participated in the study. Group differences were evaluated via inferential and Bayesian statistics (values > 1 suggest evidence for alternate hypothesis) on ASD screeners (M-CHAT at 2-years, SCQ and SRS-2 at 10-years), and gold-standard diagnostic measures (ADOS-2, ADI-R) at 10-years. Results: Males scored significantly higher than females on measures of Social Affect from the ADOS-2, t(34.27)=-2.20, BF10 = 2.33, and measures of Repetitive and Restricted Behaviors from the ADI-R, t(40.52)=-2.85, BF10 = 5.26. Bayesian estimates suggested marginal evidence for sex differences in Nonverbal Communication, t(30.66)=-1.81, BF10 = 1.25, and Verbal Communication, t(24.64)=-1.89, BF10 = 1.39, from the ADI-R, wherein males scored higher than females. No statistically significant sex differences were identified on any of the ASD screeners at 2 (M-CHAT) or 10 years (SCQ). No significant sex differences were observed on any subscales of the SRS at 10 years. Conclusions: EP autistic males present with more autistic traits than EP autistic females on gold-standard diagnostic measures of autism at 10-years of age, despite not presenting with higher autistic traits on screeners at either age. These results align with sex differences observed in full-term, autistic youth. These results suggest ASD screeners may under identify autism in EP youth, particularly females. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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