Screening and Prediction of Autism in Toddlers Using SORF in Videos of Brief Family Interactions.

The purpose of this study was to validate the utility of the Systematic Observation of Red Flags (SORF) for autism screening during 10-minute parent-child interactions at ages 15–24 months. A total of 54 children participated in this study, including 19 with autism spectrum disorder (ASD), 23 with d...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 56; no. 2; pp. 602 - 615
Autores principales: Huang, Huishi, Liu, Linru, You, Cong, Chen, Kaiyun, Xing, Yu, Li, Yijie, Deng, Hongzhu
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2026
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      pub: Springer Nature
      place: New York, New York
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        atl: Screening and Prediction of Autism in Toddlers Using SORF in Videos of Brief Family Interactions.
      aug:
        au:
          Huang, Huishi
          Liu, Linru
          You, Cong
          Chen, Kaiyun
          Xing, Yu
          Li, Yijie
          Deng, Hongzhu
        affil: https://ror.org/04tm3k558 Child Development and Behavior Center, Third Affiliated Hospital of Sun Yat-sen University, No.600, Tianhe Road, Tianhe District, Guangzhou, Guangdong Province, China
      sug:
        subj:
          Autism Spectrum Disorder Diagnosis
          Health Screening
          Early Diagnosis
          Prediction Models
          Parent-Child Relations
          Videorecording
          Sensitivity and Specificity Evaluation
          Human
          Male
          Female
          Infant
          Child, Preschool
          China
          Academic Medical Centers
          Hospitals, Pediatric
          Nonexperimental Studies
          Comparative Studies
          Descriptive Statistics
          Data Analysis Software
          One-Way Analysis of Variance
          Post Hoc Analysis
          Kruskal-Wallis Test
          ROC Curve
          Pearson's Correlation Coefficient
          Spearman's Rank Correlation Coefficient
          Sample Size Determination
          Questionnaires
          Clinical Assessment Tools
          Psychological Tests
          Reference Values
          Predictive Value of Tests
          Funding Source
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Male
          Female
      ab: The purpose of this study was to validate the utility of the Systematic Observation of Red Flags (SORF) for autism screening during 10-minute parent-child interactions at ages 15–24 months. A total of 54 children participated in this study, including 19 with autism spectrum disorder (ASD), 23 with developmental delay, and 12 typically developing children. Coders coded 10-minute videos of parent-child interactions based on the defined scoring criteria. The discriminative ability for outcome diagnosis was evaluated for total score, social communication score, restricted repetitive behavior score, number of red flags, and composite score. SORF scores demonstrated good discriminative ability between ASD and non-ASD children, with the composite score (AUC = 0.884) showing the best discriminative ability for outcome diagnosis and predicting likelihood of ASD in young children. The composite score represented a simplified measurement, with the cutoff score of 7 and sensitivity and specificity of 0.789 and 0.800, respectively. Significance: SORF has the potential to be used as an observational screening tool for ASD in children aged 15–24 months. The present study demonstrates the feasibility of brief observation, which may increase the practicality of SORF. Clinical Trial Registration: www.chictr.org.cn, identifier ChiCTR2100049811, 2021-08-10.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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