Early Diagnosis of Cognitive Impairment in the Ageing Population: Determinants and Barriers.

Background: Diagnosis of cognitive impairment at an early stage is vital to the management of dementias like Alzheimer's disease. Recent studies have proven the benefits of multimodal interventions in patients with early stages of cognitive impairment. In this study, we evaluate the determinants of...

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Publicado en:Indian Journal of Community Medicine Vol. 51; no. 1; pp. 52 - 58
Autores principales: Kumar, Pramod, Waris, Mujtaba, Rao, Abhijith R, Bajpai, Swati, Soni, Nidhi, Chakrawarty, Avinash, Chatterjee, Prasun, Dey, Aparajit Ballav
Formato: research tables/charts Journal Article
Publicado: Wolters Kluwer India Pvt Ltd Jan/Feb2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan/Feb2026
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        atl: Early Diagnosis of Cognitive Impairment in the Ageing Population: Determinants and Barriers.
      aug:
        au:
          Kumar, Pramod
          Waris, Mujtaba
          Rao, Abhijith R
          Bajpai, Swati
          Soni, Nidhi
          Chakrawarty, Avinash
          Chatterjee, Prasun
          Dey, Aparajit Ballav
        affil: Department of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India
      sug:
        subj:
          Cognition Disorders Diagnosis
          Cognition Disorders Diagnosis
          Cognition Disorders Risk Factors
          Early Diagnosis
          Risk Assessment
          Human
          Cross Sectional Studies
          Retrospective Design
          Descriptive Statistics
          Male
          Female
          Middle Age
          Aged
          Psychological Tests
          Diagnosis, Brain
          Magnetic Resonance Imaging
          Chi Square Test
          Fisher's Exact Test
          Multivariate Statistics
          Regression
          Odds Ratio
          Confidence Intervals
          India
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Diagnosis of cognitive impairment at an early stage is vital to the management of dementias like Alzheimer's disease. Recent studies have proven the benefits of multimodal interventions in patients with early stages of cognitive impairment. In this study, we evaluate the determinants of presentation of cognitive impairment at early and late stages in a tertiary center memory clinic. Study Design: A cross-sectional study. Method: A total of 438 patients presenting with cognitive impairment were evaluated in the memory clinic. After ruling out reversible causes and pseudodementia, 294 patients were included for final analysis and classified as those with early disease (i.e., Subjective Cognitive Decline [SCD] and Mild Cognitive Impairment [MCI]) or major neurocognitive decline [MNCD]. A retrospective data analysis was done to evaluate the association of baseline characteristics (age, sex, education, region, occupation, and cardiovascular diseases) with the stage of presentation of cognitive decline. Result: Patients presenting with an early-stage cognitive impairment (SCD and MCI) constituted 65% and MNCD was identified in 35% of the population. Demographic factors like female sex [OR: 1.99, 95% CI: 1.10, 3.56] and lower education [OR: 1.99, 95% CI: 1.15, 3.42] were significantly associated with late presentation MNCD. Conclusion: Female patients and those with lower education are vulnerable to late presentation and can be an important target population for dementia screening. Increasing dementia awareness and care at the primary healthcare level may help in the early diagnosis and preventive interventions of dementia.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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