Evaluating the Use of Lower Dose Flucytosine for the Treatment of Cryptococcal Meningitis: A Clinical Trial.

Background Cryptococcosis is a leading cause of death among people with human immunodeficeincy virus (HIV). Guidelines recommend combination therapy with amphotericin B and flucytosine, but standard flucytosine dosing of 100 mg/kg/day is associated with hematologic toxicity. The FLOOR trial investig...

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Bibliographic Details
Published in:Clinical Infectious Diseases Vol. 82; no. 1; pp. 67 - 75
Main Authors: Rutakingirwa, Morris K, Skipper, Caleb P, Dai, Biyue, Wele, Abduljewad, Namombwe, Suzan, Mugabi, Timothy, Ndyetukira, Jane Frances, Sadiq, Alisat, Kabahubya, Mable, Chemusto, Lenard
Format: clinical trial research tables/charts Journal Article
Published: Oxford University Press / USA 1/15/2026
Online Access:View this record in EBSCOhost