| Sumario: | Introduction: Vitiligo is an acquired skin depigmentation disorder which manifests as asymptomatic depigmented macules anywhere on the body including mucous membranes of lips and genitalia. It is very difficult to treat and mostly associated with psychological distress. Objective: The objective of the study is to demonstrate the therapeutic efficacy of individualised homoeopathic treatment in the management of vitiligo. Case summary: This is a case of vitiligo in a 20-year-old female, manifested as diffuse whitish patchy discoloration on the back of neck and behind the right ear for the last 4 years. After taking conventional mode of treatment, patient got temporary improvement but the condition recurred after discontinuing the conventional treatment. Following homoeopathic principles, Pulsatilla nigricans was prescribed. Vitiligo impact scale - 22 (VIS-22) was used to assess the patient-reported outcome, and the Modified Naranjo Criteria for Homeopathy (MONARCH) was used to assess potential causal attribution. The overall score (+9) of MONARCH substantiated the possible causal attribution to homoeopathic treatment. In this instance, the case was successfully resolved with Pulsatilla nigricans in just 10 months, with no further recurrence. Conclusion: More research with controlled trials is warranted in the future to validate the role of Homoeopathy.
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