| Sumario: | Dysentery remains a common gastrointestinal disorder in developing countries, with amoebic dysentery caused by Entamoeba histolytica constituting a significant proportion of cases. Homoeopathy offers an individualised therapeutic approach, including the use of lesser-known remedies. This case report aims to demonstrate the therapeutic role and clinical efficacy of Holarrhena antidysenterica in the management of acute amoebic dysentery and to document symptom resolution and recovery following its administration. A 32-year-old male presented with frequent mucoid stools occasionally streaked with blood, abdominal colic, tenesmus, dehydration, and irritability. Based on symptom similarity and Materia Medica considerations, Holarrhena antidysenterica 30C was prescribed. Marked clinical improvement was observed within 48 hours, followed by complete recovery. This report highlights the effectiveness of Holarrhena antidysenterica in dysentery, underscores the importance of non-reportorial, Materia Medica--based individualised homoeopathic prescribing, and encourages greater clinical utilisation and further research into indigenous homoeopathic medicines.
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