Implantable Neural Speech Decoders: Recent Advances, Future Challenges.

The social life of locked-in syndrome (LIS) patients is significantly impacted by their difficulties to communicate. Consequently, researchers have started to explore how to decode intended speech from neural signals directly recorded from the cortex. The first studies in the late 2000s reported mod...

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Publicado en:Neurorehabilitation & Neural Repair Vol. 40; no. 2; pp. 157 - 173
Autores principales: Jhilal, Soufiane, Marchesotti, Silvia, Thirion, Bertrand, Soudrie, Brigitte, Giraud, Anne-Lise, Mandonnet, Emmanuel
Formato: review tables/charts Journal Article
Publicado: Sage Publications Inc. Feb2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2026
      vid: 40
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Implantable Neural Speech Decoders: Recent Advances, Future Challenges.
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          Jhilal, Soufiane
          Marchesotti, Silvia
          Thirion, Bertrand
          Soudrie, Brigitte
          Giraud, Anne-Lise
          Mandonnet, Emmanuel
        affil: Institut Pasteur, Université Paris Cité, Hearing Institute, IHU reConnect, Paris, France
      sug:
        subj:
          Speech Production Measurement Equipment and Supplies
          Brain-Computer Interfaces
          Electrodes, Implanted
          Artificial Intelligence
          Neural Pathways
          Cerebral Cortex
          Communication
          Paralysis
          Locked-In Syndrome
          Dysarthria, Hyperkinetic
          Machine Learning
          Algorithms
          Action Potentials
          Electroencephalography
          Phonology
          Speech Acoustics
          Vocabulary
          Infarction
          Brain Stem Pathology
          Amyotrophic Lateral Sclerosis
      ab: The social life of locked-in syndrome (LIS) patients is significantly impacted by their difficulties to communicate. Consequently, researchers have started to explore how to decode intended speech from neural signals directly recorded from the cortex. The first studies in the late 2000s reported modest decoding accuracies. However, thanks to fast advances in machine learning, the most recent studies have reached decoding accuracies high enough to be optimistic about the clinical benefit of neural speech decoders in the near future. We first discuss the selection criteria for implanting a neural speech decoder in LIS patients, emphasizing the advantages and disadvantages associated with conditions such as brainstem stroke and amyotrophic lateral sclerosis. We examine the key design considerations for neural speech decoders, demonstrating how successful implantation requires careful optimization of multiple interrelated factors including language representation, cortical recording areas, neural features, training paradigms, and decoding algorithms. We then discuss current approaches and provide arguments for potential improvements in decoder design and implementation. Finally, we explore the crucial question of who should learn to use the neural speech decoder—the patient, the machine, or both. In conclusion, while neural speech decoders present promising avenues for improving communication for LIS patients, interdisciplinary efforts spanning neurorehabilitation, neuroscience, neuroengineering, and ethics are imperative to design future clinical trials.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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