Dosimetric Validation and Surface Fit Evaluation of 3D-Printed Dose Boluses for Radiation Therapy Applications.

Background: In modern radiation therapy, accurate dose delivery to tumor sites while sparing surrounding healthy tissue is paramount. A dose bolus, commonly employed to modulate surface dose distribution, ensures effective treatment. Objectives: The present study focuses on the dosimetric validation...

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Publicado en:International Journal of Cancer Management Vol. 18; no. 1; pp. 1 - 10
Autores principales: Ghediri, Noussaiba, Kharfi, Faycal, Benkahila, Karim, Boulkhessaim, Foued, Meziri, Amina, Betka, Abderrahim, Khelfa, Sara
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Medical Journals Commission of the Ministry of Health & Medical Education Jan-Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan-Dec2025
      vid: 18
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      pub: Medical Journals Commission of the Ministry of Health & Medical Education
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        10.5812/ijcm-159515
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        atl: Dosimetric Validation and Surface Fit Evaluation of 3D-Printed Dose Boluses for Radiation Therapy Applications.
      aug:
        au:
          Ghediri, Noussaiba
          Kharfi, Faycal
          Benkahila, Karim
          Boulkhessaim, Foued
          Meziri, Amina
          Betka, Abderrahim
          Khelfa, Sara
        affil: Department of Physics, Setif-1-University-Ferhat Abbas, Setif, Algeria
      sug:
        subj:
          Dosimetry
          Radiation Dosage
          Radiotherapy Equipment and Supplies
          Radiotherapy, Computer-Assisted
          Printing, Three-Dimensional
          Treatment Outcomes
          Quality of Health Care
          Human
          Validation Studies
          Funding Source
          Case Studies
      ab: Background: In modern radiation therapy, accurate dose delivery to tumor sites while sparing surrounding healthy tissue is paramount. A dose bolus, commonly employed to modulate surface dose distribution, ensures effective treatment. Objectives: The present study focuses on the dosimetric validation of 3D-printed dose boluses by comparing their effective performances to the targeted ones when creating the virtual boluses by the clinician on the treatment planning system (TPS). Methods: The research involves the fabrication of 3D-printed boluses using flexible thermoplastic polyurethane filament (TPU) and the assessment of their dose delivery accuracy using "Eclipse" and "Monaco" TPS. By considering 3 treatment cases and clinical locations, namely: Frontal lobe, right breast and inguinal region, the validation process was based on the measurement and comparison of dose profiles across the air/bolus/tissue interfaces, dose coverage: D98%, D95%, D50%, D2% and Dmean, dose Homogeneity Index (HI), and dose Conformity Index (CI). How boluses fit the received surfaces was also checked through CT scanning. Results: The results demonstrate that 3D-printed boluses offer superior conformity to patient-specific anatomy, leading to improved surface dose distribution. Overall, the 3D-printed boluses exhibit optimal dosimetric performances that conform to the targeted ones, with the added benefits of customization and ease of production. Conclusions: This study highlights the potential of 3D printing technology to enhance radiation therapy by providing flexible, patient-specific solutions for the fabrication of dose bolus while maintaining the dosimetric integrity required for an effective and accurate treatment.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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