More Than an Abscess: Vancomycin-Associated Resolution of Suspected Pyoderma Gangrenosum in Ulcerative Colitis.
A 46-year-old man with a 5-year history of ulcerative colitis presented with a rapidly progressive ulcer on the left ankle, presumed to be a methicillin-resistant Staphylococcus aureus abscess. Despite multiple courses of antibiotics and surgical drainage, the lesion did not improve; imaging and cul...
| Publicado en: | ACG Case Reports Journal Vol. 13; no. 1; pp. 1 - 4 |
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| Autor principal: | |
| Formato: | case study pictorial Journal Article |
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American College of Gastroenterology
Jan2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191570589&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191570589 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23263253 HJC2 jtl: ACG Case Reports Journal issn: 23263253 maglogo: N pubinfo: dt: Jan2026 vid: 13 iid: 1 pid: 94678 pub: American College of Gastroenterology place: Bethesda, Maryland artinfo: ui: 191570589 191570589 191570589 10.14309/crj.0000000000001977 191570589 ppf: 1 ppct: 3 formats: tig: atl: More Than an Abscess: Vancomycin-Associated Resolution of Suspected Pyoderma Gangrenosum in Ulcerative Colitis. aug: au: Sasse, Ryan affil: University of Missouri-Kansas City School of Medicine, Kansas City, MO sug: subj: Colitis, Ulcerative Pyoderma Gangrenosum Diagnosis Pyoderma Gangrenosum Drug Therapy Male Middle Age Ulcer Etiology Physical Examination Methicillin-Resistant Staphylococcus Aureus Wound Care Emergency Service Tomography, X-Ray Computed Ultrasonography, Doppler Osteomyelitis Venous Thrombosis Vancomycin Therapeutic Use Administration, Intravenous Wound Healing Treatment Outcomes Patient Discharge Cephalexin Therapeutic Use Administration, Oral Pain Erythema Middle Aged: 45-64 years Male ab: A 46-year-old man with a 5-year history of ulcerative colitis presented with a rapidly progressive ulcer on the left ankle, presumed to be a methicillin-resistant Staphylococcus aureus abscess. Despite multiple courses of antibiotics and surgical drainage, the lesion did not improve; imaging and cultures remained negative for infection. Empiric intravenous vancomycin was given, after which the patient reported improvement in pain and erythema, although no pathogen was identified. Considering an active inflammatory bowel disease flare, lesion characteristics, sterile cultures, and mild pathergy, pyoderma gangrenosum (PG) was considered retrospectively. Although histopathology was not obtained, the clinical context strongly favored PG. This case underscores the diagnostic challenge and potential harm of misidentifying PG as infection. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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