Improvement and Implementation Science to Optimize Statin Therapy in Primary Prevention.

Supplemental Digital Content is Available in the Text. Introduction: Less than 1/5th of eligible patients are prescribed statins for primary prevention in the United States. Methods: We conducted a quality improvement program augmented by contextually responsive implementation strategies (IS), Plan-...

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Publicado en:Journal for Healthcare Quality: Promoting Excellence in Healthcare Vol. 48; no. 1; pp. 1 - 12
Autores principales: Acharya, Sameer, Senner, Jillian, Ejaz, Kanwal, Pokharel, Yashashwi
Formato: research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Jan-Mar2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan-Mar2026
      vid: 48
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Improvement and Implementation Science to Optimize Statin Therapy in Primary Prevention.
      aug:
        au:
          Acharya, Sameer
          Senner, Jillian
          Ejaz, Kanwal
          Pokharel, Yashashwi
      sug:
        subj:
          Quality Improvement
          Implementation Science
          Statins Therapeutic Use
          Needs Assessment
          Health Services Accessibility
          Primary Health Care
          Preventive Health Care
          Human
          New York
          Adult
          Middle Age
          Aged
          Internal Medicine
          Group Processes
          Discussion
          Consensus
          Lipids Blood
          Descriptive Statistics
          Coronary Arteriosclerosis Risk Factors
          Risk Assessment
          Atherosclerosis Prevention and Control
          Hospitals, Community New York
          Mortality Prevention and Control
          Coronary Arteriosclerosis Prevention and Control
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
      ab: Supplemental Digital Content is Available in the Text. Introduction: Less than 1/5th of eligible patients are prescribed statins for primary prevention in the United States. Methods: We conducted a quality improvement program augmented by contextually responsive implementation strategies (IS), Plan-Do-Study-Act cycles, and Lean Six Sigma Principles to optimize statin therapy among 40–75-year-old patients without atherosclerotic cardiovascular diseases (ASCVD) in primary prevention in resident internal medicine clinic. We conducted needs assessment; identified process measures, barriers to statin optimization using discussions; and rank ordered these barriers. We mapped multiple IS to the barriers using discussions/consensus over 2 years. We retrofitted the IS to the Expert Recommendations for Implementing Change (ERIC) taxonomy to facilitate IS reporting. Results: We noted significant improvement in process measures such as lipid panel orders (64.6% vs. 95.5%), its completion (78.6% vs. 95.3%), ASCVD risk score completion (3% vs. 91%), and statin therapy optimization (34.5% vs. 90%) over 2 years among eligible patients (baseline vs. final cohort, respectively; all p ≤.001). Conclusions: Using improvement and implementation science to identify needs assessment, process measures, and barriers in statin optimization and mapping IS to the barriers can help improve statin optimization in primary prevention. Our reporting of IS using the ERIC taxonomy should further help operationalize IS in other contexts.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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