Effects of health technology use and digital health engagement on clinical trial Participation: Findings from the Health Information National Trends Survey.
Background/Aims: The existing literature indicates that clinical trial knowledge and participation is multifactorial, yet little is known about the association with digital health technology use and digital health engagement. To address this gap, we examined the multivariate association between clin...
| Published in: | Clinical Trials Vol. 23; no. 1; pp. 43 - 54 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Sage Publications, Ltd.
Feb2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191613667&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191613667 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17407745 AB6 jtl: Clinical Trials issn: 17407745 maglogo: N pubinfo: dt: Feb2026 vid: 23 iid: 1 pid: 33180 pub: Sage Publications, Ltd. place: <Blank> artinfo: ui: 191613667 189777166 191613667 191613667 10.1177/17407745251387981 191613667 ppf: 43 ppct: 11 formats: tig: atl: Effects of health technology use and digital health engagement on clinical trial Participation: Findings from the Health Information National Trends Survey. aug: au: Peiper, Nicholas C Furmanek, Stephen McCants, Kelly C Brown Jr, Edward H affil: Department of Epidemiology & Population Health, University of Louisville, Louisville, KY, USA sug: subj: Digital Health Clinical Trials Digital Technology Utilization Health Knowledge Research Subject Recruitment Patient Participation Human Appointments and Schedules United States Surveys Stratified Random Sample Adolescence Adult Middle Age Confidence Intervals Health Information Communication Cross Sectional Studies Aged Aged, 80 and Over Male Female Educational Status Descriptive Statistics Data Analysis Software Funding Source Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background/Aims: The existing literature indicates that clinical trial knowledge and participation is multifactorial, yet little is known about the association with digital health technology use and digital health engagement. To address this gap, we examined the multivariate association between clinical trial knowledge and participation with past-year health technology use and digital health engagement with medical providers using data from a federal surveillance system in the United States. Methods: A total of 3865 US adult respondents from the Health Information National Trends Survey 5, Cycle 4 provided data in 2020. The two outcomes were clinical trial knowledge (no knowledge, a little knowledge, a lot of knowledge) and participation (never invited, invited did not participate, invited and participated). There were four binary indicators of health technology use for the following purposes in the past year: searching for health or medical information, communicating with a doctor's office, looking up medical test results, and making medical appointments. There were four binary indicators of digital health engagement in the past year: sharing health information on social media, participating in a health forum or support group, watching health-related videos on YouTube, and awareness of ClinicalTrials.gov. Results: Survey-weighted multivariate regression models demonstrated that awareness of ClinicalTrials.gov had the greatest associations with clinical trial knowledge (adjusted risk ratio = 7.60, 95% confidence interval: 4.82–12.00) and participation (adjusted risk ratio = 2.60, 95% confidence interval: 1.23–5.54). Using digital technology to look for health information (adjusted risk ratio = 1.35, 95% confidence interval: 1.06–1.71) and communicate with doctor's offices were significantly associated with higher clinical trial knowledge (adjusted risk ratio = 1.64, 95% confidence interval: 1.25–2.14). Involvement in an online forum or support group was significantly associated with an increased likelihood of being invited but not participating in a clinical trial (adjusted risk ratio = 2.32, 95% confidence interval: 1.22–4.39), while using digital technology to make medical appointments was significantly associated with an increased likelihood of clinical trial participation (adjusted risk ratio = 1.79, 95% confidence interval: 1.07–2.99). Conclusions: Findings from this study can inform the design of large-scale digital health campaigns and quality improvement programs focused on increasing clinical trial participation. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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