In Silico Evaluation of Natural Compounds as Inhibitors of the Oropouche Virus Gc Glycoprotein.

Introduction: Oropouche virus (OROV) is an emerging orthobunyavirus in the Americas with no approved antiviral therapies. Methods: This work employed a structure-based in-silico pipeline to identify natural compounds with potential to inhibit the Gc glycoprotein, a class II fusion protein essential...

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Bibliographic Details

Published in:	Salud Uninorte pp. 94 - 96
Main Authors:	VARGAS-ECHEVERRÍA, CARLOS, SAURITH-CORONELL, OSCAR, RODRIGUEZ-MACÍAS, JUAN, BRAZÓN, EDGAR A. MÁRQUEZ, MORA, JOSÉ R., FUENTES-GANDARA, FABIO, PAZ, JOSÉ L., SALAZAR, FRANKLIN
Format:	Article
Published:	Fundacion Universidad del Norte 2025 Special Issue
Subjects:	Glycoproteins Phytochemicals Bunyaviruses Virtual high-throughput screening (Drug development) Antiviral agents Molecular dynamics Molecular docking Americas
Online Access:	View this record in EBSCOhost