Best Practice Expert Opinion and Guidelines for Assessing Blood Pressure Stability in Clinical Trials and Foundational Research After Spinal Cord Injury.
Spinal cord injury (SCI) and the associated autonomic dysfunction often lead to unique and severe blood pressure instability, including low resting blood pressure, orthostatic hypotension, postprandial hypotension, and transient episodic hypertension. Despite the high prevalence of these complicatio...
| Publicado en: | Topics in Spinal Cord Injury Rehabilitation Vol. 32; no. 1; pp. 51 - 72 |
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| Autores principales: | , , , , , , |
| Formato: | pictorial practice guidelines Journal Article |
| Publicado: |
KnowledgeWorks Global, Ltd
Winter2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191766939&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191766939 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10820744 0OF jtl: Topics in Spinal Cord Injury Rehabilitation issn: 10820744 maglogo: N pubinfo: dt: Winter2026 vid: 32 iid: 1 pid: 81084 pub: KnowledgeWorks Global, Ltd place: Richmond, Virginia artinfo: ui: 191766939 191766939 191766939 10.46292/sci25-00021 191766939 ppf: 51 ppct: 21 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Best Practice Expert Opinion and Guidelines for Assessing Blood Pressure Stability in Clinical Trials and Foundational Research After Spinal Cord Injury. aug: au: Phillips, Aaron A. Huh, Sungchul McKenna, Stephan Trbovich, Michelle Hagen, Ellen Merete Slocum, Chloe Wecht, Jill affil: Departments of Physiology and Pharmacology, Clinical Neurosciences, Cardiac Sciences, Libin Cardiovascular Institute, Hotchkiss Brain Institute, RestoreNetwork, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada sug: subj: Spinal Cord Injuries Physiopathology Blood Pressure Physiology Blood Pressure Determination Methods Clinical Trials Clinical Research Expert Clinicians Consensus Practice Guidelines Telehealth Monitoring, Physiologic Hypotension, Orthostatic Postprandial Period Hypotension Autonomic Dysreflexia Relaxation Patient Positioning ab: Spinal cord injury (SCI) and the associated autonomic dysfunction often lead to unique and severe blood pressure instability, including low resting blood pressure, orthostatic hypotension, postprandial hypotension, and transient episodic hypertension. Despite the high prevalence of these complications and the associated negative clinical outcomes, standardized protocols for measuring blood pressure stability in SCI clinical trials and research remain lacking. This guidelines article outlines best practices for measuring blood pressure stability in the SCI population. The guidelines were developed through a comprehensive literature review in combination with expert consensus to describe the techniques and necessary considerations when assessing blood pressure stability in individuals with SCI. We include detailed and rationalized protocols for assessing resting blood pressure, orthostatic hypotension, postprandial hypotension, and autonomic dysreflexia in individuals with SCI. An emphasis is placed on using validated and standardized tools, meticulous preparation, and practical and safe measurement techniques as well as careful consideration and mitigation of the myriad of confounding factors unique to the SCI population. We also advocate for integrating at-home monitoring and mobile health technologies to provide continuous, real-world data on blood pressure stability. Implementing best practice guidelines will enhance the accuracy and reliability of blood pressure assessments in SCI clinical settings and research, thereby facilitating the detection of cardiovascular dysfunction and ultimately improving patient outcomes. This comprehensive framework aims to advance our scientific understanding and clinical management of cardiovascular autonomic dysfunction after SCI, ultimately contributing to better health and quality of life for this population. pubtype: Academic Journal doctype: pictorial practice guidelines Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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