Reproducibility and accuracy of non-contrast abbreviated magnetic resonance imaging of the liver in surveillance for early recurrence for hepatocellular carcinoma in a Western population: a multi-reader study.
Purpose: Abbreviated MRI (AMRI) protocols may represent an alternative to conventional MRI (CMRI) for surveillance of hepatocellular carcinoma (HCC). We aimed to compare the inter-reader agreement and sensitivity of AMRI versus CMRI for HCC recurrence < 2 years after curative ablation in at risk-pop...
| Published in: | Abdominal Radiology Vol. 51; no. 2; pp. 702 - 714 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Feb2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=191808269&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 191808269 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Feb2026 vid: 51 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 191808269 186487383 10.1007/s00261-025-05105-5 191808269 ppf: 702 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Reproducibility and accuracy of non-contrast abbreviated magnetic resonance imaging of the liver in surveillance for early recurrence for hepatocellular carcinoma in a Western population: a multi-reader study. aug: au: Rimola, Jordi Saborido, Belén Igual, Alba Roca, Andreu Darnell, Anna Jiménez, Sergio Mesa, Alicia Navarro, Vicente Soler, Alexandre Ayuso, Carmen Reig, María affil: https://ror.org/02a2kzf50 BCLC Group, Radiology Department, Hospital Clínic de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain sug: ab: Purpose: Abbreviated MRI (AMRI) protocols may represent an alternative to conventional MRI (CMRI) for surveillance of hepatocellular carcinoma (HCC). We aimed to compare the inter-reader agreement and sensitivity of AMRI versus CMRI for HCC recurrence < 2 years after curative ablation in at risk-population. Methods: Eight radiologists (4 with < 5 years' and 4 with ≥ 5 years' experience) from three institutions reviewed a retrospective serie of 143 CMRI and AMRI from 75 cirrhotic patients (84% HCV and/or alcohol-related) undergoing secondary screening after HCC ablation in a blinded and independent manner, with imaging assessments separated by 1–3 month. We calculated the intra and inter-reader agreement by means Gwet's AC1 for detection of local recurrence at the ablation site, new intrahepatic, and any type of recurrence (either local and/or new intrahepatic) with CMRI and AMRI. Reference diagnoses of recurrent HCC were based on histological or imaging-based criteria. Results: Early HCC recurrence was detected in 37 (49.3%), including 12 local recurrence, 21 new intrahepatic lesions, 4 had both local recurrence and new intrahepatic lesions. Inter-reader agreement was similarly high for AMRI and CMRI for local recurrence [0.87 (0.83‒0.90) vs. 0.87 (0.83‒0.92)], but higher for AMRI than for CMRI for new intrahepatic [0.85 (0.81‒0.9) vs. 0.6 (0.52‒0.67)] and any type [0.73 (0.67‒0.78) vs. 0.56 (0.49‒0.64)] recurrences. Sensitivity for detecting any type of HCC recurrence was higher for CMRI [0.83 (0.78‒0.87) vs. 0.39 (0.33‒0.45) for AMRI, p < 0.0001]. Conclusions: Compared to CMRI, non-contrast AMRI showed higher inter-observed agreement but with very low sensitivity for early detection of HCC recurrence in a cohort with predominantly HCV and/or alcohol related cirrhosis, making it not suitable for this purpose. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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