Barriers to Same-Day Pre-exposure Prophylaxis (PrEP) Implementation in Federally Funded HIV Clinics Within High-Burden Areas of the U.S.: A Coincidence Analysis.

Background: Same-day pre-exposure prophylaxis (PrEP) for HIV prevention is a novel tool to increase biomedical prevention access and uptake. Although prior research has identified same-day PrEP as feasible and acceptable, improved understanding of key barriers and facilitators to implementation is n...

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Publicado en:AIDS & Behavior Vol. 30; no. 2; pp. 558 - 571
Autores principales: Zamantakis, Alithia, Gomez, Wilson, Lukose, Lipin, Pachicano, Ana Michaela, Kassanits, Jessica, Katomski, Anna-Sophia, Rosenberg-Carlson, Elena P., Willging, Cathleen E., Nelson, LaRon E., Valeriano, Tequetta, Karris, Maile, Blumenthal, Jill S., Rana, Aadia I., Brewer, Russell A., Hamilton, Alison, Kemp, Christopher, Humphries, Debbie, Benbow, Nanette D., Kao, Uyen, Lee, Sung-Jae
Formato: research tables/charts Journal Article
Publicado: Springer Nature Feb2026
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Barriers to Same-Day Pre-exposure Prophylaxis (PrEP) Implementation in Federally Funded HIV Clinics Within High-Burden Areas of the U.S.: A Coincidence Analysis.
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        au:
          Zamantakis, Alithia
          Gomez, Wilson
          Lukose, Lipin
          Pachicano, Ana Michaela
          Kassanits, Jessica
          Katomski, Anna-Sophia
          Rosenberg-Carlson, Elena P.
          Willging, Cathleen E.
          Nelson, LaRon E.
          Valeriano, Tequetta
          Karris, Maile
          Blumenthal, Jill S.
          Rana, Aadia I.
          Brewer, Russell A.
          Hamilton, Alison
          Kemp, Christopher
          Humphries, Debbie
          Benbow, Nanette D.
          Kao, Uyen
          Lee, Sung-Jae
        affil: https://ror.org/000e0be47 Institute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA
      sug:
        subj:
          Pre-Exposure Prophylaxis
          HIV Infections Prevention and Control
          Health Services Accessibility
          Financing, Government
          United States
          Human
          Implementation Science
          Data Analysis Software
          Public Health
          Community Health Centers
          Funding Source
          Descriptive Statistics
      ab: Background: Same-day pre-exposure prophylaxis (PrEP) for HIV prevention is a novel tool to increase biomedical prevention access and uptake. Although prior research has identified same-day PrEP as feasible and acceptable, improved understanding of key barriers and facilitators to implementation is needed to optimize impact. Methods: The Network for Implementation Science in HIV (NISH) examined the implementation of same-day PrEP across 42 Ryan White Part A-D-funded organizations in seven Ending the U.S. HIV Epidemic Initiative priority jurisdictions. We used crisp-set coincidence analysis with six conditions to identify key barriers explaining delayed implementation of same-day PrEP among 38 clinical organizations representing 137 individual clinics where same-day PrEP services were available currently or in the future. Results: Our final model explained ~ 67% of clinical organizations not currently implementing same-day PrEP (n = 8), with a consistency of 80%. This model identified three pathways to non-implementation of same-day PrEP: (1) insurance coverage as a top barrier and insufficient staffing resources as a top barrier; (2) no onsite pharmacy as a top barrier; or (3) provider reticence with same-day PrEP prescribing and insurance coverage as top barriers, and patient demand/(dis)interest in same-day PrEP not being ranked as a top barrier. Conclusion: The three identified pathways to delayed implementation of same-day PrEP aid researchers and providers in reverse mapping strategies to enhance and scale up the implementation of same-day PrEP in federally funded clinics in the U.S. Such strategies may include federal and state-level policy changes to expand funding for PrEP coverage, pharmacist-led same-day PrEP implementation, or mail delivery of PrEP prescriptions.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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