From Tanzania to Washington, DC: Application of the Consolidated Framework for Implementation Research and ADAPT-ITT Model to Guide the Development of a Community-Based PrEP Intervention for Black Adults.

While HIV incidence in Washington, DC has declined overall, significant racial disparities persist. Pre-exposure prophylaxis (PrEP) remains underutilized among Black adults due to multiple barriers including medical mistrust, stigma, and structural barriers to access. Using the Consolidated Framewor...

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Published in:AIDS & Behavior Vol. 30; no. 2; pp. 611 - 625
Main Authors: Tun, Waimar, Gomez-Berrospi, Jennifer, Janson, Samuel, Hickson, Demarc, Morris, Christian, Pulerwitz, Julie, Kopeka, Mamaswatsi, Yao, Jesse, Mixson, Rikiyah, McHale, Amanda, Macey, Rachel, Buchanan, Christian, Rinola, Bukola, Koranteng-Yorke, Naana, Kerrigan, Deanna, Bamodu, Oluwaseun Adebayo, Conserve, Donaldson F.
Format: research tables/charts Journal Article
Published: Springer Nature Feb2026
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
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        atl: From Tanzania to Washington, DC: Application of the Consolidated Framework for Implementation Research and ADAPT-ITT Model to Guide the Development of a Community-Based PrEP Intervention for Black Adults.
      aug:
        au:
          Tun, Waimar
          Gomez-Berrospi, Jennifer
          Janson, Samuel
          Hickson, Demarc
          Morris, Christian
          Pulerwitz, Julie
          Kopeka, Mamaswatsi
          Yao, Jesse
          Mixson, Rikiyah
          McHale, Amanda
          Macey, Rachel
          Buchanan, Christian
          Rinola, Bukola
          Koranteng-Yorke, Naana
          Kerrigan, Deanna
          Bamodu, Oluwaseun Adebayo
          Conserve, Donaldson F.
        affil: https://ror.org/03zjj0p70 Population Council, Washington, DC, USA
      sug:
        subj:
          Conceptual Framework
          Community Health Services
          Pre-Exposure Prophylaxis
          African Americans Psychosocial Factors
          Implementation Science
          HIV Infections Prevention and Control
          Human
          Qualitative Studies
          Ajzen's Theory of Planned Behavior
          Interviews
          Thematic Analysis
          Content Analysis
          Descriptive Statistics
          Data Analysis Software
          District of Columbia
          Purposive Sample
          Snowball Sample
          Tanzania
          Medical Mistrust
          Stigma
          Health Services Accessibility
          Telehealth
          Privacy and Confidentiality
          Funding Source
          Male
          Female
          Adult
          Adult: 19-44 years
          Male
          Female
      ab: While HIV incidence in Washington, DC has declined overall, significant racial disparities persist. Pre-exposure prophylaxis (PrEP) remains underutilized among Black adults due to multiple barriers including medical mistrust, stigma, and structural barriers to access. Using the Consolidated Framework for Implementation Research (CFIR) and ADAPT-ITT model, we conducted in-depth interviews with opinion leaders (n = 28) including community-based organization leaders, health department representatives, healthcare providers, and current/potential PrEP users to guide the adaptation of a community-based HIV treatment intervention from Tanzania to create a community-based PrEP intervention for Black adults in Washington, DC to address the aforementioned barriers. Data analysis employed thematic content analysis with CFIR construct mapping to identify implementation barriers and facilitators. Key implementation facilitators included: mobile service delivery in high-need areas (Wards 7–8), comprehensive health service integration, culturally matched staffing, flexible evening/weekend hours, and multi-channel outreach via social media and community venues. Major barriers included privacy concerns in mobile settings, social determinants of health challenges, and multilayered stigma. Drawing on these findings, we developed the adapted cbPrEP intervention with the six components featuring: (1) mobile service delivery platform, (2) comprehensive service integration, (3) community-centered staffing model, (4) privacy and confidentiality protocols, (5) multi-channel outreach strategy, and (6) wraparound support services including insurance navigation. This study demonstrates the value of using implementation science frameworks to adapt evidence-based interventions while centering community voices. The resulting cbPrEP intervention model shows promise for increasing PrEP access among Black adults in Washington, DC through culturally responsive, community-based service delivery.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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