Cost-Effectiveness of Internet-Delivered Emotion Regulation Therapy for Adolescents With Nonsuicidal Self-Injury: Within-Trial Analysis of a Randomized Controlled Trial.

Background: Nonsuicidal self-injury (NSSI) is common among adolescents and is associated with adverse clinical outcomes, as well as suicidal behavior. Current treatments are resource-intensive and may not be accessible to all adolescents with NSSI. Internet-delivered emotion regulation individual th...

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Publicado en:JMIR Mental Health Vol. 12; pp. 1 - 18
Autores principales: Bjureberg, Johan, Ojala, Olivia, Rasmusson, Björn, Malmgren, Jessica, Hellner, Clara, Sampaio, Filipa, Flygare, Oskar
Formato: research tables/charts Journal Article
Publicado: JMIR Publications Inc. 2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2025
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      pub: JMIR Publications Inc.
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        atl: Cost-Effectiveness of Internet-Delivered Emotion Regulation Therapy for Adolescents With Nonsuicidal Self-Injury: Within-Trial Analysis of a Randomized Controlled Trial.
      aug:
        au:
          Bjureberg, Johan
          Ojala, Olivia
          Rasmusson, Björn
          Malmgren, Jessica
          Hellner, Clara
          Sampaio, Filipa
          Flygare, Oskar
        affil: Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Norra Stationsgatan 69, Stockholm, Sweden
      sug:
        subj:
          Injuries, Self-Inflicted Therapy
          Internet-Based Intervention Economics
          Emotional Regulation
          Behavior Therapy Economics
          Individualized Medicine
          Health Care Costs
          Cost Effectiveness Analysis
          Human
          Adolescence
          Acceptance and Commitment Therapy Economics
          Sweden
          Injuries, Self-Inflicted Epidemiology
          Injuries, Self-Inflicted Prevention and Control
          Quality-Adjusted Life Years Evaluation
          Clinical Assessment Tools
          Descriptive Statistics
          Confidence Intervals
          Mental Health Services In Adolescence
          Male
          Female
          Self Report
          Linear Regression
          Adolescent: 13-18 years
          Male
          Female
      ab: Background: Nonsuicidal self-injury (NSSI) is common among adolescents and is associated with adverse clinical outcomes, as well as suicidal behavior. Current treatments are resource-intensive and may not be accessible to all adolescents with NSSI. Internet-delivered emotion regulation individual therapy for adolescents (IERITA) with NSSI disorder is a promising treatment option, but its cost-effectiveness is unknown. Objective: This study aims to evaluate the cost-effectiveness of IERITA for adolescents with NSSI disorder. Methods: Within-trial cost-effectiveness analysis of a randomized controlled trial at three child and adolescent mental health services in Sweden (n=166). A total of 12 weeks of IERITA plus treatment as usual (TAU) versus TAU only were compared. The primary outcome was the frequency of NSSI at 1-month posttreatment. Secondary outcomes were NSSI remission and quality-adjusted life years (QALYs). Results: IERITA led to reductions in NSSI frequency, a higher proportion of participants with NSSI remission, and more QALYs at 1-month posttreatment, at additional health care costs of US $3663 (95% CI US $2182-$5002) and societal costs of US $4458 (95% CI US $−577 to $9509). The incremental cost of one additional NSSI remission at 1-month posttreatment was US $18,677, and the incremental cost per QALY gained was US $792,244 for IERITA+TAU relative to TAU. IERITA had an 8% probability of being cost-effective at a societal willingness-to-pay threshold of US $84,000 for one QALY at 1-month posttreatment, which increased to 18% at 3-months posttreatment. Conclusions: IERITA delivered adjunctive to TAU led to improvements in NSSI frequency, remission, and QALYs, at additional costs compared to TAU only. This study provides an estimate of the additional cost of delivering IERITA; however, future studies should include longer follow-up periods to better assess the magnitude of the effects on QALYs and societal costs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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