Glucose control among women with gestational diabetes and early offspring's growth.

Objective. To assess the association between glucose control during pregnancy and infant's growth. Materials and methods. Prospective study of 130 women with gestational diabetes mellitus (GDM) followed up to three months after birth. Infant's growth was assessed as weight-for-age (WfA), weight-for-...

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Publicado en:Salud Pública de México Vol. 68; no. 1; pp. 43 - 52
Autores principales: Parra-Cabrera, María Socorro, Hurtado-Salgado, Erika Marlen, Monterrubio-Flores, Eric, Méndez-Gómez-Humarán, Ignacio, Cupul-Uicab, Lea Aurora
Formato: Artículo
Publicado: Instituto Nacional de Salud Publica ene/feb2026
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      dt: ene/feb2026
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        10.21149/16423
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        atl: Glucose control among women with gestational diabetes and early offspring's growth.
      aug:
        au:
          Parra-Cabrera, María Socorro
          Hurtado-Salgado, Erika Marlen
          Monterrubio-Flores, Eric
          Méndez-Gómez-Humarán, Ignacio
          Cupul-Uicab, Lea Aurora
        affil:
          Center for Population Health Research, National Institute of Public Health. Cuernavaca, Morelos, Mexico
          Center for Nutrition and Health Research, National Institute of Public Health. Cuernavaca, Morelos, Mexico
          Center for Research in Mathematics AC Aguascalientes. Aguascalientes, Mexico
      su:
        Gestational diabetes
        Blood sugar
        Infant growth
        Pancreatic beta cells
        Hyperglycemia
      sug:
        subj:
          Gestational diabetes
          Blood sugar
          Infant growth
          Pancreatic beta cells
          Hyperglycemia
      keyword:
        control de glucosa
        crecimiento infantil
        diabetes mellitus gestacional
        estudio prospectivo
        gestational diabetes mellitus
        glucose control
        hijos
        infant's growth
        offspring
        prospective study
        control de glucosa
        crecimiento infantil
        diabetes mellitus gestacional
        estudio prospectivo
        hijos
      ab:
        Objective. To assess the association between glucose control during pregnancy and infant's growth. Materials and methods. Prospective study of 130 women with gestational diabetes mellitus (GDM) followed up to three months after birth. Infant's growth was assessed as weight-for-age (WfA), weight-for-length (WfL), and length-for-age (LfA) z-scores. The association of adequate vs. inadequate glucose control with infant's growth was evaluated using linear mixed models. Results. Overall, glucose control during pregnancy was not associated with WfA (aβ= 0.089; 95%CI: -0.248,0.426), WfL (aβ= 0.006; 95%CI: -0.280,0.291), and LfA (aβ= 0.136; 95%CI: -0.157,0.429). We observed heterogeneity of effects by gestational age; infants with adequate control compared to inadequate had reduced WfA if they were born at ≥39 weeks. Conclusion. Glucose control of women with GDM might have little impact on their early offspring's growth; however, gestational age might be relevant in terms of heterogeneity of effects. Future studies to confirm the latter findings are required.
        Objetivo. Evaluar la asociación del control de glucosa en el embarazo con el crecimiento infantil. Material y métodos. Estudio prospectivo de 130 mujeres con diabetes gestacional (DG) y sus productos. Crecimiento infantil determinado como puntuaciones-z de peso para la edad (PE), peso para la longitud (PL) y longitud para la edad (LE). La asociación del control adecuado (vs. inadecuado) de glucosa y crecimiento se evaluó con modelos lineales mixtos. Resultados. El control de glucosa no se asoció con PE (βa= 0.089; IC95%: -0.248,0.426), PL (βa= 0.006; IC95%: -0.280,0.291) y LE (βa= 0.136; IC95%: -0.157,0.429). Se observó heterogeneidad de efectos por edad gestacional; aquellos con control adecuado comparado con inadecuado tuvieron PE reducido si nacieron a las ≥39 semanas. Conclusión. El control de glucosa en mujeres con DG parece tener poco impacto en el crecimiento temprano de sus hijos; sin embargo, la edad gestacional parece ser relevante. Se requieren estudios para confirmar estos hallazgos.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2026
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